Immunology Flashcards
(31 cards)
Produced by plasma cells via B-cells
Antibodies
Cytotoxic T-cells
Identify viral infected cells for destruction
Lupus
AB - Antigen complexes clog the filtering organs
Contain MHC that acts to ‘present’ the invader antigen to the killer and helper T-cells
APC’s Antigen presenting cells
AB class that is activated as first defense and binds complement activators
IgM
Often follow infection d/t supercharged immune system response
Autoimmune
Arise from stem cells, give rise to plasma and memory cells
B-cells
Prevents attacking self cells, B-cells and T-cells both bind to confirm antigen is foreign
MHC
Activates B cells and killer T-cells Directs actions of proteins and cytokines
Helper T-cells
Tag foreign antigens for destruction
Antibodies
Rash, inflammation, kidney damage d/t IgG attacking self antigens - affects primarily women
Lupus
Kiss of death
Process by which a pathogen is marked for death Opsonization
Allergic response- parasite defense Made after first exposure
IgE
Cell surface protein that presents antigen to T-cells as foreign
MHC Major histocompatibility complex
IgE AB d/t antigen Mast cells degranulate releasing histamine
Allergies Hay fever, asthma etc
Myasthenia gravis
Poliovirus protein is similar to Ach receptor causing immune response
Macrophages stimulate TNF that damages joint spaces
RA
Neutralizes viruses Life span of 3 weeks
IgG
RA
Autoimmune damage to joints = inflammation of cartilage protein - IgM/IgG complexes
Alpha, beta, gamma receptors
T-cells Recognize the antigen
AB class that traverses the digestive tract and collects pathogens to eliminate thru poops
IgA
MHC molecules presenting peptides derived from self or B/T cells have receptors for self antigen
Autoimmune
Immune cells attack beta cells of pancreas- cytotoxic T-cells attack pancreas
IDDM
Function of AB binding
Prevent virus from entering cells