Immunology Flashcards

(31 cards)

1
Q

Produced by plasma cells via B-cells

A

Antibodies

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1
Q

Cytotoxic T-cells

A

Identify viral infected cells for destruction

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1
Q

Lupus

A

AB - Antigen complexes clog the filtering organs

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2
Q

Contain MHC that acts to ‘present’ the invader antigen to the killer and helper T-cells

A

APC’s Antigen presenting cells

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3
Q

AB class that is activated as first defense and binds complement activators

A

IgM

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4
Q

Often follow infection d/t supercharged immune system response

A

Autoimmune

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6
Q

Arise from stem cells, give rise to plasma and memory cells

A

B-cells

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6
Q

Prevents attacking self cells, B-cells and T-cells both bind to confirm antigen is foreign

A

MHC

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7
Q

Activates B cells and killer T-cells Directs actions of proteins and cytokines

A

Helper T-cells

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8
Q

Tag foreign antigens for destruction

A

Antibodies

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9
Q

Rash, inflammation, kidney damage d/t IgG attacking self antigens - affects primarily women

A

Lupus

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10
Q

Kiss of death

A

Process by which a pathogen is marked for death Opsonization

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11
Q

Allergic response- parasite defense Made after first exposure

A

IgE

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11
Q

Cell surface protein that presents antigen to T-cells as foreign

A

MHC Major histocompatibility complex

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11
Q

IgE AB d/t antigen Mast cells degranulate releasing histamine

A

Allergies Hay fever, asthma etc

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12
Q

Myasthenia gravis

A

Poliovirus protein is similar to Ach receptor causing immune response

12
Q

Macrophages stimulate TNF that damages joint spaces

14
Q

Neutralizes viruses Life span of 3 weeks

15
Q

RA

A

Autoimmune damage to joints = inflammation of cartilage protein - IgM/IgG complexes

16
Q

Alpha, beta, gamma receptors

A

T-cells Recognize the antigen

18
Q

AB class that traverses the digestive tract and collects pathogens to eliminate thru poops

19
Q

MHC molecules presenting peptides derived from self or B/T cells have receptors for self antigen

20
Q

Immune cells attack beta cells of pancreas- cytotoxic T-cells attack pancreas

22
Q

Function of AB binding

A

Prevent virus from entering cells

24
The central function of adaptive immunity
Antigen presentation
25
AB class that brings killer cells to the target Good opsonizer
IgG
26
Initial infection attack - complement activator! Life span 1 day
IgM
28
Guards mucosal cells Abundant
IgA
29
Antibodies against self NMJ Ach receptors Ach is blocked from binding- results in weakness
Myasthenia gravis
30
AB class that increase immune activity and whose binding to allergen causes mast cell to degranulate
IgE
31
Function of B-cells
1. Produces 1 type of AB 2. Recognizes and binds many foreign substances