Immunology Flashcards Preview

Microbiology-1 > Immunology > Flashcards

Flashcards in Immunology Deck (143)
Loading flashcards...
1

The cells and molecules responsible for immunity, and their collective and coordinated response to the presence of foreign substances.

Immune System

2

The overall actions of the immune system to provide immunity through a sequence of integrated host defense events when a host encounters a "foreign" substance and leading to cellular and chemical defensive actions.

Immune Response

3

The body's resistance to disease-causing microorganisms and damage by foreign substances.

Immunity

4

Natural/native immunity. Non-specific, general recognition & response to "foreign" substances, including inflammatory response.

Innate Host Response

5

The route of transmission & microbe type determine nature of response.

Innate Host Response

6

This is the acquired/induced response

Adaptive immunity

7

Adaptive Response is _____ to "foreign" substances.

Specific

8

Pre-committed lymphocytes in the lymph nodes and spleen respond against the "foreign" substance

Adaptive immunity

9

A foreign substance, such as a microorganism, foreign blood cell, cells of transplanted organs, or toxins.

Antigen (Ag)

10

What triggers an immune response when introduced into the body?

Antigen (Ag)

11

What is the basic molecule of an antibody?

Y shaped

12

Antibody portion that is antigen-specific, and binds to a specific site on antigen molecules and assists in inactivating the antigen by attaching to it.

Fragment Antigen-Binding (Fab)

13

Part of the antibody that can bind to a phagocytic cell.

Fc portion

14

What is categorized into classes: Ig A, Ig D, Ig E, Ig G, Ig M?

Antibody (Ab) [immunoglobulin Ig]

15

Antigen specific proteins

Antibody (Ab) [immunoglobulin Ig]

16

What do phagocytes do?

ingest and digest invading microbes
1. Ingestion
2. Digestion
3. Waste

17

Phagocytes are certain _____ blood cells

white

18

Specialized cells located in various tissues that help initiate the immune response by recognizing, "processing", and presenting Ag to other cells of the immune system

Dendritic cell

19

Where do stem cells originate?

Bone marrow

20

About how many erythrocytes are there per mcL?

4-6 million

21

About how many leukocytes are there per mcL?

4,500-11,000

22

Which white blood cells are involved in the inflammatory process?

Basophiles (0.5-1%)

23

Which white blood cells increase in allergic responses?

Eosinophils (1-5%)

24

What are the primary phagocytic cells that ingest/kill foreign material?

Neutrophils (45-75%)

25

About how many hours do neutrophils circulate for?

6-10 hours

26

What do neutrophils do after they circulate in the blood?

adhere to the endothelium of the blood vessels and wait to respond to inflammation; short lived.

27

What matures into macrophages & dendritic cells and responds to inflammation signals?

Monocyte (2-8%)

28

What are precommitted during maturation to respond to specific antigens?

Lymphocytes (25-40%)

29

What are the types of lymphocytes?

T-cell, B-cell, and Natural Killer Cell

30

Approximately, how many lymphocytes are produced per day?

10^9