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Indication --> Drug Flashcards

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1
Q

Dyspepsia

A

Aluminium and Magnesium Hydroxide with Calcium Carbonate

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2
Q

Heartburn

A

Aluminium and Magnesium Hydroxide with Calcium Carbonate

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3
Q

Gastric Reflux

A

Sodium Alginate with NaHCO

Omeprazole (PPI)

Lansoprazole (PPI)

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4
Q

Stomach Ulcer

A

Ranitidine (H2- Antagonist)

Cimetidine (H2 - Antagonist)

Omeprazole (PPI)

Lansoprazole (PPI)

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5
Q

Duodenal Ulcer

A

Omeprazole (PPI)

Lansoprazole (PPI)

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6
Q

Pancreatic Insufficiency

A

Pancreatin (Enzymes)

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7
Q

Cystic Fibrosis

A

Pancreatin (Enzymes)

Dornase Alfa (Mucolytic)
Carbocisteine (Mucolytic)
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8
Q

Pancreatitis

A

Pancreatin (Enzymes)

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9
Q

Constipation

A

Methylcellulose (Bulk)

Isphagula Husk (Bulk)

Docusate (Softener)

Arachis Oil (Softener)

Macrogol (Osmotic)

Lactulose (Osmotic)

Mg Sulphate (Osmotic)

MgOH (Osmotic)

Bisacodyl (Stimulant)

Senna (Stimulant)

Picosulfate (Stimulant)

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10
Q

Diarrhoea

A

Loperamide (Opioid Anti Motility)

Codeine (Opioid Anti Motility)

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11
Q

Left Ventricular Heart Failure

A

Furosemide (decrease BP)

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12
Q

Oedema

A

Furosemide

Bendroflumethiazide

Spironolactone

Epleronone

Amiloride

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13
Q

Hypertension

A 
THIAZIDES
Indapamide
Bendroflumethiazide
Chlorthalidone
Hydrochlorothiazide 
ACEi
Ramipril
Captopril
Perindopril
Lisinopril

ARBs
Losartan
Valsartan
Irbesartan
Candesartan

Renin Inhibitor - Aliskiren

B BLOCKERS
Bisoprolol
Atenolol
Metaprolol
Propranolol
Labetalol

A-1 BLOCKER
Doxazosin

A-2 Agonist
Clonidine

CCB
Amlodipine
Nifedipine
Diltiazem

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14
Q

Congestive Heart Failure

A

POTASSIUM SPARING
Spironolactone
Eplerenone
Amiloride

Digoxin (Cardiac Glycoside)

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15
Q

Cerebral Oedema

A

Mannitol

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16
Q

Intra-Ocular Pressure

A

Mannitol (Osmotic)

Acetazolamide (CAi)

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17
Q

Open and Acute Closed Angle Glaucoma

A

Acetazolamide (CAi)

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18
Q

Diabetic Nephropathy

A 
ACEi 
Ramipril
Captopril
Perindopril
Lisinopril

ARBs
Losartan
Valsartan
Irbesartan
Candesartan

Decrease Vasocontriction and lower BP

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19
Q

Heart Failure

A 
ACEi
Ramipril
Captopril
Perindopril
Lisinopril

ARBs
Losartan
Valsartan 
Irbesartan
Candesartan

Ivabradine

GTN
ISMN

Sacubitril (Neprilysin Inhib) with ARB For reduces EF

NITRATES
GTN
ISMN

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20
Q

Stable Angina

A

B BLOCKER
Bisoprolol
Atenolol
Propranolol

CCB
Amlodipine
Nifedipine
Diltiazem

Ivabradine (normal sinus)

ANTI-PLATELETS
Aspirin
Clopidogrel
Prasugrel
Ticagrelor
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21
Q

Benign Prostatic Hyperplasia (BPH)

A

Doxazosin (A blocker)

Tamsulosin (A 1 blocker)

Finasteride (Anti-Androgens)

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22
Q

Acute Angina Pectoralis

A

GTN

ISMN

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23
Q

Cardiac Arrest

A 
SYMPATHOMIMETICS
Adrenaline
Dobutamine
Noradrenaline
Metaraminol
Isoprenaline
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24
Q

Cardiogenic Shock

A 
SYMPATHOMIMETICS
Adrenaline
Dobutamine
Noradrenaline
Metaraminol
Isoprenaline
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25
Cardiovascular Disease Relief
ANTIPLATELETS Aspirin Clopidogrel
26
Anticoagulant Prophylaxis
ANTIPLATELET Aspirin Clopidogrel
27
Deep Vein Thrombosis
``` ANTICOAGULANT Warfarin (Vit Ki) Apixiban (FXai) Rivaroxaban (FXai) Edoxaban (FXai) ```
28
Prophylaxis of Stroke from AF
``` ANTICOAGULANT Warfarin (Vit Ki) Apixaban (FXai) Edoxaban (FXai) Rivaroxaban (FXai) ```
29
Prophylaxis of Venous Thromboembolism post-surgery
Dabigatran (Thrombin i)
30
Prophylaxis of Venous Thrombosis and PE
``` ANTICOAGULANTS (Heparins) Dalteparin Tinzaparin Enoxaparin Unfractioned Heparin ```
31
MI
THROMBOLYTICS/FIBRINOLYTICS Alteplase Streptokinase Urokinase
32
Ischaemic Stroke
THROMBOLYTICS/FIBRINOLYTICS Alteplase Streptokinase Urokinase ASPIRIN (Acute)
33
Hypercholesterolaemia
HMG-CoA Reductase i Simvastatin Atorvastatin Rosuvastatin PPAR-Alpha Activator - Fenofibrate
34
CVD and Stroke Risk
HMG-CoA Reductase i Simvastatin Atorvastatin Rosuvastatin ``` ANTI PLATELETS Aspirin Clopidogrel Prasugrel Ticagrelor ```
35
Ventricular and Supraventricular Arrythmias
Disopyramide (Class 1a) Quinidine (Class 1a) Amiodarone (Class 3) Dronedarone (Class 3) Sotalol (Class 3)
36
CPR
IV Lidocaine (Class 1b) ``` IV Amiodarone (Class 3) IV Dronedarone (Class 3) IV Sotalol (Class 3) ```
37
Paroxysmal AF
Flecaininde (Class 1c) | Propafenone (Class 1c)
38
Ventricular Ectopic Beats
Flecaininde (Class 1 c) | Propafenone (Class 1c)
39
Prophylaxis of Paroxysmal Atrial Tachycardia
Atenolol (Class 2) | Bisoprolol (Class 2)
40
Prophylaxis of Paroxysmal AF
Atenolol (Class 2) | Bisoprolol (Class 2)
41
Nodal Tachyarrythmias
Amiodarone (Class 3) Dronedarone (Class 3) Sotalol (Class 3)
42
Atrial Fibrilation
Amiodarone (Class 3) Dronedaron (Class 3) Sotalol (Class 3) Digoxin (Cardiac Glycoside)
43
Supraventricular Tachycardia (Atria or AV node) | Atrial Flutter, AF, Paroxysmal SVT
Verapamil (Class 4) Diltiazem (Class 4) Adenosine
44
Arrythmias Generally
Digoxin ( Cardiac Glycoside)
45
Emergency Bradycardia
Atropine (Antimuscarininc)
46
Emergency Arrythmia
IV Magnesium Sulfate
47
Asthma Management
Salbutamol (B2-Ag) Terbutaline (B2-Ag) Salmeterol (B2-Ag) Formoterol (B2-Ag) Beclomethasone (Glucocorticoid) Prednisolone (Glucocorticoid) Hydrocortisone (Glucocorticoid) Fluticasone (Glucocorticoid) Montelukast (Leuk antag) Zafirlukast (Leuk antag)
48
Reversible Airway Obstruction
Salbutamol (B2-Ag) Terbutaline (B2-Ag) Salmeterol (B2-Ag) Formoterol (B2-Ag) Theophylline (Methylxanthine) Aminophylline (Methylxanthine)
49
Acute Asthma
Ipratropium (Antimusc) Tiotropium (Antimusc) Glycopyrronium (Antimusc) Aclidinium (Antimusc) Theophylline (MX) Aminophylline (MX)
50
Bronchospasm in COPD
Ipratropium (Antimusc) Tiotropium (Antimusc) Glycopyrronium (Antimusc) Aclindinium (Antimusc)
51
Allergic Rhinitis
Beclomethasone (Gluc) Prednisolone (Gluc) Hydrocortisone (Gluc) Fluticasone (Gluc) Montelukast (Leuk-Antag) Zafirlukast (Leuk-Antag)
52
Parkinson's Disease
``` DOPAMINERGICS Levodopa Pramipexole Ropinirole Rotigotine ``` DOPA-DECARBOXYLASE INHIBITOR (increase levodopa) Carbidopa Benserazide MAOI (increase dopamine) Selegiline Rasagaline COMT INHIBITOR (increase dopamine) Entacapone Tolcapone ANTICHOLINERGICS Orphenadrine Procyclidine Trihexphenidyl
53
Muscle Rigidity
ANTICHOLINERGICS Orphenadrine Procyclidine Trihexphenidyl
54
Side-effects of anti-psychotics
ANTICHOLINERGICS Orphenadrine Procyclidine Trihexphenidyl
55
Huntingdon's Chorea
DOPAMINE-DEPLETING DRUGS | Tetrabenazine
56
Depression
``` SSRI Sertraline Fluoxetine Citalopram Paroxetine ``` RIMA Moclobemide TCA Amitriptyline Nortriptyline Dosulepin ``` ATYPICAL Venlafaxine Reboxetine Buproprion Agomelatine Mirtazepine ```
57
Generalised Anxiety Disorder
``` SSRI Sertraline Fluoxetine Citalopram Paroxetine ```
58
Schizophrenia
Antipsychotics 1st Generation - Chlorpromazine - Haloperidol Antipsychotics 2nd Generation - Olanzapine - Risperidone - Quetiapine - Clozapine - Amisulpride
59
Bipolar
Lithium Carbonate
60
Alzheimer's Disease
CHOLINESTERASE INHIBITORS Donepezil Galantamine Rivastigmine NMDA RECEPTOR ANTAGONIST Memantine
61
Mild to Moderate Dementia
CHOLINESTERASE INHIBITORS Donepezil Galantamine Rivastigmine
62
Moderate to Severe Dementia
NMDA RECEPTOR ANTAGONIST | Memantine
63
Anxiety and Related Disorders
ANXIOLYTICS Buspirone ``` BENZODIAZEPINES Lorazepam Midazolam Diazepam Zolpidem ```
64
Insomnia
Zopiclone (Non-benzo hypnotic)
65
Epilepsy
``` ANTI-EPILEPTICS Sodium Valproate Lamotrigine Carbemazepine Ethosuximide Topiramate Levetiracetam Phenytoin ``` ``` BENZODIAZEPINES Lorazepam Midazolam Diazepam Zolpidem ``` BARBITURATES Phenobarbitone Pentobarbitone Primidone
66
Acute Seizures
``` BENZODIAZEPINES Lorazepam Midazolam Diazepam Zolpidem ``` BARBITURATES Phenobarbitone Pentobarbitone Primidone
67
Reversal of Benzodiazepine Sedation
Flumazenil
68
Mild-Moderate Pain
Paracetamol (weak analgesic) Codeine (opioid) Dihydrocodeine (opioid) Naproxen (NSAID) Ibuprofen (NSAID) Diclofenac (NSAID) Etoricoxib (COX2) Celecoxib (COX2)
69
Pyrexia
Paracetamol
70
Inflammation
Naproxen (NSAID) Ibuprofen (NSAID) Diclofenac (NSAID) Etoricoxib (COX2) Celecoxib (COX2)
71
Severe Pain
``` Morphine (opioid) Diamorphine (opioid) Pethidine (opioid) Fentanyl (opioid) Oxycodone Remifentanil ```
72
Moderate to Severe Pain
Buprenorphine Pentazocine Tramadol
73
Opiate Overdose
Naloxone | Naltrexone
74
Respiratory Depression
Naloxone | Naltrexone
75
Opiate Addiction
Methadone | Buprenorphine
76
Neuropathic Pain
Gabapentin Pregabalin Amitriptyline
77
Analgesia During Childbirth
Nitrous Oxide + Oxygen
78
Induction of anaesthesia throughout major surgery
``` GENERAL ANAESTHETICS Propofol Isoflurane Sevoflurane Ketamine ```
79
Local Anaesthesia
Lidocaine Bupivacaine Levobupivacaine
80
Tracheal Intubation and mechanical ventilation during surgery
``` NEUROMUSCULAR BLOCKERS Atracurium besilate Vecuronium Suxamethonium Rocuronium ```
81
Immediate reversal of NMB to reduce post-operative pulmonary complications
Sugammadex (Reversing Neuromuscular Block)
82
Myasthenia Gravis
Neostigmine (Reversing Neuromuscular block)
83
Maintaining sedation and relaxed muscle tone
Temazepam (BDZ) Zolpidem Dexmedetomidine (a-2-ag) Alfentanil (opioid) Fentanil Remifentanil
84
Nausea and Vomiting
Cyclizine (H1 receptor blockade) Domperidone (D2 receptor blockade) Metoclopramide (D2 receptor blockade) Ondansetron (5-HT3 receptor block)
85
Respiratory Infection (Bacterial)
Penicillins (Beta Lactam) - Amoxicillin - Co-Amoxiclav - Piperacillin-Tazobactam - Flucloxacillin - Phenoxymethylpenicillin
86
Pneumonia (Bacterial)
Penicillins (Beta Lactam) - Amoxicillin - Co-amoxicillin - Piperacillin-Tazobactam - Flucloxacillin - Phenomethylpenicillin Macrolide Antibiotic - Erthromycin - Azithromycin
87
H. Pylori
Penicillins (Beta Lactam) - Amoxicillin - Co-amoxiclav - Piperacillin-Tazobactam - Phenoxymethylpenicillin - Flucloxacillin
88
Bacterial Meningitis
Carbapenems (Beta Lactam) - Meropenem Cephalosporins (Beta Lactam) - Ceftriaxone
89
Hospital-Acquired Septicaemia
Carbapenems (Beta Lactam) | - Meropenem
90
Gram-negative infections
Cephalosporins (Beta Lactam) | - Ceftriaxone
91
UTI
Antifolate Antibiotic - Trimethoprim Nitrofuran - Nitrofurantoin
92
Bacterial Respiratory Tract Infection
Fluoroquinolones | - Ciprofloxacin
93
Community Acquired Pneumonia
Tetracycline Antibiotic | - Doxycycline
94
Ophthalmic Infection
Aminoglycoside | - Gentamycin
95
C. Difficile Infection
Glycopeptide | - Vancomycin
96
Anaerobic Bacterial Infection: Leg ulcers, Pressure sores
Nitroimidazole (anti-anaerobe) | - Metronidazole
97
Tuberculosis
Antituberculosis Drugs (used in combination) - Isoniazid (inhib of bac wall synth) - Ethambutol (inhib of bac wall synth) - Rifampicin (inhib of mycobac RNA synth) - Pyrazinamide
98
Hepatitis B and C
Therapeuric Cytokines | - Interferon Alpha (activate immune response)
99
Herpes simplex infection
DNA Polymerase Inhibitors (virus rep block) - Aciclovir - Ganciclovir
100
Influenza Viral Infection
Neuraminidase Inhibitors | - Oseltamivir
101
Hepatitis C and RSV
``` Nucleoside Analogue (disrupt viral RNA synth) - Ribavirin ```
102
HIV Infection
Nucleoside reverse transcriptase inhibitor - Tenofovir - Nevirapine Non-nucleoside reverse transcriptase inhibitors - Efavirenz Viral Protease inhibitor - Lopinavir - Ritonavir Viral Entry Inhibitor - Maraviroc Integrase Inhibitor - Dolutegravir Viral fusion inhibitor - Enfuviritide
103
Candida Infection
Anti-fungal - Fluconazole - Clotrimazole
104
Type 1 Diabetes Mellitus
``` Insulin Glargine (long) Insulin Linspro (rapid) Insulin Aspart (short) ```
105
Type 2 Diabetes Mellitus
``` Insulin Glargine (long) Insulin Linspro (rapid) Insulin Aspart (short) ``` GLP-1 Agonist - Exenatide - Liraglutide SGLT-2 Inhibitor - Dapigaflozin - Canagliflozin Oral Biguanide - Metformin - increases insulin sensitivity - inhibits hepatic gluconeogenesis Sulphonylurea - Gliclazide - Stimulates pancreatic insulin secretion Thiazolidinedione - Pioglitazone - increases insulin sensitivity in muscle and adipose GLP-1 agonist - Exenatide - incretin (blood glucose reducer) hormone analogue DPP-4 inhibitor - Sitagliptin - Reduces inactivation of incretins Lipase inhib - Orlistat - Inhib of GI fat uptake
106
Obesity
Lipase Inhib - Orlistat
107
Hypothyroidism
``` Levothyroxine Sodium (T4) Liothyronine Sodium (T3) ```
108
Rheumatoid Arthritis
Antifolate Antiproliferative - Methotrexate Thiopurine Antiproliferative - Azathioprine - 6-Mercaptopurine Antimetabolite Antiproliferative - Leflunomide Cytokine Modulators - Adalimumab - Etanercept - Infliximab Aminosalicylates - Sulfasalazine - Mesalazine
109
Crohn's Disease
Thiopurine Antiproliferative - Azathioprine - 6-Mercaptopurine Cytokine Modulators TNF-Alpha block - Adalimumab - Etanercept - Infliximab Aminosalicylates - Sulfasalazine - Mesalazine
110
Hormonal Contraception
Oral combination pill - Desogestrel and Ethinylestradiol Oral mini-pill Progesterone only - Desogestrel - Levonorgestrel (emergency) Implants - Etonogestrel Progesterone Receptor Modulator (Emergency) - Ulipristal
111
PCOS
Oral combination pill | - Desogestrel and Ethinylestradiol
112
Menopause
HRT - Estradiol - Noresthisterone - Medroxyprogesterone
113
Delay in Labour
Induction of Labour - Dinoprostone Augmentation Agents - Oxytocin
114
Termination of Pregnancy
Antiprogestogen/Prostaglandin | - Mifepristone with Misoprostol
115
Menorrhagia
Antifibrinolytic | - Tranexamic Acid
116
Dysmenorrhoea
NSAID | - Mefenamic Acid
117
Benign Prostatic Hyperplasia
Alpha-1-blocker - Tamsulosin Anti-Androgen - Finasteride
118
Urinary Retention
Alpha-1-Blocker | - Tamsulosin
119
Overactive Bladder
Antispasmodic (AntiACh) - Oxybutynin - Solifenacin - Tolterodine Beta-3-Agonist - Mirabegron
120
Hay Fever
Anti-Histamine | - Chlorphenamine
121
Urticaria
Anti-Histamine | - Chlorphenamine
122
Suppression of Inflammatory Diseases (Crohn's, RA)
Glucocorticoids - Prednisolone - Hydrocortisone - Dexamethasone
123
Solid Organ Transplantation
Calcineurin Inhibitor - Cyclosporin - Tacrolimus Inosine Monophosphate Dehydrogenase Inhibitor - Mycophenolate
124
Eczema (topical)
Calcineurin Inhibitor - Cyclosporin - Tacrolimus
125
Broad spectrum of Malignancies
Classical Alkylating Agent - Cyclophosphamide Taxanes - Paclitaxel - Docetaxel Vinca Alkaloids - Vincristine - Vinblastine Antifolates - Methotrexate Antipyramidines - Fluorouracil - Cytarabine Antipurines - Mercaptopurine - Thioguanine Anthracycline Antibiotics - Doxorubicin
126
Early Breast Cancer
Antineoplastic MAB | - Trastuzumab
127
Folicular Lymphoma
Antineoplastic MAB | - Rituximab
128
Non-Hodgkin's Lymphoma
Antineoplastic MAB | - Rituximab
129
Melanoma
Antineoplastic MAB | - Nivolumab
130
Breast Cancer
SERM | - Tamoxifen
131
Prostate Cancer
LHRH receptor agonist | - Goserelin
132
Osteoporosis
Therapeutic Calcitonin Hormone Bisphosophates - Alendronate - Pamidronate - Risedronate Denosumab (MAB)
133
Hypercalcaemia
Therapeutic Calcitonin Hormone Bisphosphonates - Alendronate - Pamidronate - Risedronate
134
Hypocalcaemia
Drugs for Hypocalcaemia - IV calcium gluconate - Vitamin D - PTH
135
Bone Loss
Drugs for Hypocalcaemia - IV calcium gluconate - Vitamin D - PTH
136
Vitamin D Deficiency
Vitamin D - Colecalciferol - Calcitriol - 1,25-dihydroxyvitamin D
137
Prevention of Bone Fractures
Selective oestrogen receptor modulator (SERM) for osteoporosis - Raloxifene
138
Iron-Deficient Anaemia
Ferrous Sulphate
139
Folate-deficient anaemia
Folic Acid
140
Pernicious Anaemia
Hydroxocobalamin (B12 enzyme co-factor)
141
Paracetamol Overdose
N-Acetylcysteine
142
Severe Alcohol Misuse
GABA Activators Chlordiazepoxide Clomethiazole Acamprosate
143
Migraine
Sumatriptan (onset) | Topiramate (prophylaxis)
144
Bone and Joint Infections
Lincosamide - Clindamycin
145
Threadworm
Mebendazole (Anti-helmintic)
146
Hookworm
Mebendazole (Anti-helmintic)
147
Scabies
Permethrin (Pyrethrine) Topical
148
Elevated Triglycerides
PPAR-Alpha Activator | - Fenofibrate
149
Diabetes Insipidus
Desmopressin
150
Hyperthyroidism
Anti-Thyroids - Propylthiouracil - Carbimazole
151
Acute Gout
Colchicine
152
Gout Prophylaxis
Xanthine Oxidase inhibitors - Allopurinol - Febuxostat
153
Chronic Gout
Indometacin (NSAID)
154
Neutropaenia
Synthetic G-CSF | - Filgrastim
155
Severe Acne
Retinoids - Acitretin - Isotretinoin
156
Psoriasis
Retinoids - Acitretin - Isotretinoin
157
Myeloma
Immunomodulator | - Lenolidamide
158
Follicular Lymphoma
Antineoplastic mab | - Rituximab

Drugs List Phase 3 (5 decks)

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