Infection prevention Flashcards

1
Q

Give an example of an environmental source of infection
Is onward transmission possible?
Where is it found?

A
  • Legionella pneumophila
  • Found in contaminated water
  • Onward transmission is not possible
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2
Q

Give an example of a food/water source of infection
Is onward transmission possible? (3)

A

Food poisoning (gastroenteritis) organisms ie listeria monocytogenes, E.coli, salmonella
- Onward transmission is possible

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3
Q

Give an example of an animal source of infection
Is onward transmission possible? (2)

A
  • Rabies
  • COVID - 19
  • Onward transmission is possible
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4
Q

Name some diseases that (direct) person to person transmission is the predominant mode of transmission (3)

A

Influenza
Norovirus
Neisseria gonorrhoea

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5
Q

An example of Person to person indirect transmission

A

Mosquitos (vector) for malaria

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6
Q

What are the consequences of transmission?

A
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7
Q

What’s endemic disease? What is it dependant on?

A

The Usual background rate of infection
- Dependant on the time of year

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8
Q

What’s an outbreak?

A

Two or more cases linked in time and place

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9
Q

What’s an epidemic?

A

A rate of infection greater than the usual background rate

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10
Q

What’s a pandemic?

A

Very high rate of infection spreading across many regions, countries and continents

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11
Q

What is R0 (basic reproduction number)?

A
  • Average number of cases one case generates
  • over its infectious period
  • in an otherwise uninfected non-immune population
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12
Q

What does it mean if R0 >1

A

Increase in cases

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13
Q

What does R0 = 1 mean

A

Stable number of cases

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14
Q

What does R0 <1

A

Decrease in cases

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15
Q

Reasons for outbreaks, epidemics, pandemics

A
  • New pathogen (eg antigens, virulence factors, antibacterial resistance)
  • New hosts (eg, non-immunes, healthcare effects)
  • New practice (IV drug use/move to new area)
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16
Q

What factors determine transmissibility? (3)

A
  • Infectious dose
    (number of microorganisms required to cause infection)
  • The method of spread - ?airborne/aerosol? Droplets ?direct contact (shingles) ?sexual encounter (i.e. mucous membranes)
  • Immunity status of the host ie immunocompromised
17
Q

What does infectious dose vary with? (3)

A
  • Microorganism type
  • Presentation of micro-organism - how are you exposed to it? (aerosol, food, blood borne)
  • Immunity of potential host
18
Q

What does an epidemic curve look like?

A

Smooth curve up, reaches peak and comes back down

19
Q

Why is the epidemic curve smooth?

A

Pattern of transmission:

Susceptible –> infected –> Recovered (with immunity)

20
Q

What pattern do small scale outbreaks (ie a ward) follow?

A

Stochastic curve

Irregular and unpredictable

21
Q

Why can the stochastic nature of small scale outbreaks be misleading?

A

as people can form conclusions without considering the fact that this may normally occur without any interventions!

22
Q

Interventions (pathogens) (5)

A
23
Q

Interventions (patient) (6)

A

.

24
Q

What is herd immunity? (3)

A
  • Large portion of a community (the herd) becomes immune to a disease.
  • The spread of disease from person to person becomes unlikely when herd immunity is achieved
  • Thus the whole community becomes protected — not just those who are immune.
25
Q

Why is herd immunity important?

A

Prevents onward transmission

26
Q

Practice interventions (10)

A
27
Q

Place interventions (4)

A
28
Q

Good consequences of control.
Give 3 examples

A

Decreased insidence/eliminated disease/organism (polio, smallpox dracunliasis)

29
Q

Bad consequences of control (2)

A

.

30
Q

Name some conditions that if you got them at a later age, they would be more severe (4)

A
  • Chicken pox
  • Congenital rubella syndrome
  • Hepatitis A
  • Polio
31
Q

How can we keep a balance of good and bad consequences?

A

Surveillance:

  • What is happening now, here and elsewhere
    AND
  • What might happen - be aware of risks