Infections

Question 1

Stick injury from HBV, HCV AND HIV

Answer 1

HBV: 6-30%
HCV: 1%
HIV: 0.3%

Question 2

Vertical transmission of HBV, HCV AND HIV

Answer 2

HBV: 10-90%
HCV: 3%
HIV: 1%

Question 3

When do PEPSE initiated after HIV exposure

Answer 3

24 hrs up to 72 h

Question 4

What kind of PEP used in pregnant woman?

Answer 4

Efavirenz or atazanavir 1st line
Raltegravir 400mg bd as third agent

Question 5

What PEP to avoid if at risk of pregnancy or within 1st 6 weeks

Answer 5

Dolutegravir (if she is already taking it and after 6w dont stop it)
Antiretroviral used for PEP is CI in pregnancy

Question 6

Doultegravir recommended dose

Answer 6

50 mg of from 6 w

Question 7

Women taking dolutegravir trying to concieve or <12 w shall take

Answer 7

Folic acid 5 gm od

Question 8

When to prescribe tenofovir as PEP

Answer 8

After 1st trimester

Question 9

Woman presented >28 w and VL>100,000 what to give

Answer 9

Three or gour drug regimen includes raltegravir 400 mg bd or doultegravir 50mg od

Question 11

The decrease in risk of hiv transmission to 1% is d.t

Answer 11

1 .the use of highly active anti retroviral therapy (HAART)
2.appropriate management of delivery
3.avoidance of breastfeeding.

Question 12

Ho wlong it takes HIV antibodies to appear following infection

Answer 12

3 months

Question 13

Woman in labour with unknown HIV status, what to do

Answer 13

Rapid HIV test takes 20 min

Question 14

Antiretroviral agents

Answer 14

1.nucleoside RT inhibitors: Zidovudine, Tenofovir, Emtricitabin, Didanosin, Abacavir, Lamivudin

2.non-nucleoside RT inhibitors: Efavirenz, Nevirapine

3.A protease inhibitors: Indinavir

Question 15

What to do before starting ART for new diagnosed HIV

Answer 15

1. Sexual health screening
2. LFTs
3. HIV Resistance testing except >28 w
4. CD4 cell count then at delivery

Question 16

When to test HIV vir

Question 17

How long should she be considered infectious after exposure of chickenpox

Answer 17

If took VZIG: 8-28
If not: 8-21