Twin pregnancy Flashcards
(70 cards)
Incidence of multiple pregnancy?
3% of lofe birth
how many od successful IFV results in twins
1/4
24%
maternal mortality im multiple compared to singleton
2.5 times more
incidence of PTL in twins
up to 50%
TTTs accounts for what percent of stillbirth
20%
66% of stillbirth in twin has IUGR - 39% in singleton
Of twins, how many are dichorionic and monochorionic ?
DC: 70%
MC: 30%
For a twin pregnancy, what do you see on the 1st trimester ultrasound?
11-14+1 w
Gestational age - determine GA from largest twin to avoid estimating it from a baby with early growth pathology
Chorionicity and amnionicity
Before 14 wks
Number of placental masses
Membrane thickness
Lambda & T sign
After 14 weeks
Additional - fetal sex
+ screening for trisomy
Determin chorioniciy in twins by us using:
- Number of placental masses
- Membrane thickness
- Lambda & T sign
- gender >14w
Lambda sign seen in ?
DCDA
T sign is seen in
MCDA
What if difficult to detect chorionicity or amnionicity ?
- 2nd opinion from senior or
- Referral to a competent health-care professional
If still difficult after referral - manage as monochorionic
when determining chorionicity, if TAS is difficult d.t. high BMI or RVF
use TVS
not 3d
Due to high risk of anemia in multiple pregnancy, when do you perform an additional CBC apart from at booking and 28 wks ?
20-24 W then 28w
early supplement w/ iron or folic acid
How many antenatal appointments for
DCDA twins ?
TC TA triplets ?
Twins or triplets with a shared chorion ?
Twins or triplets with a shared amnion ?
8
9
11
Shared amnion - Individualise from tertiary level fetal medicine unit
How do you screen for chromosomal anomalies in twins ?
Same as singleton
TWINS:
1st 11-14+1w : Age + Combined (NT+PAPPA+BHCG)
2nd: Age+ Quadrable (HIAE HCG+Inhibin+AFP+E3)
Triplets:
1st: age+NT
2nd: no test
How do you screen for chromosomal anomalies in triplets?
Maternal age + NT
No 2nd trimester serum markers
For screening of dichorionic and monochorionic triplets- refer to fetal medicine
interpretation of the result of down syn screening in twins
if >1:150: refer to FMU
How many twin & triplet pregnancies have a spontaneous Preterm birth ?
60% before 37 wks for twins
75% before 35 wks for triplets
How is monitoring for FGR done ?
Can it be done in the 1st trimester ?
- SFH and abdominal palpation not used
- Ultrasound done
- 24 wks onwards - in TriTri and DiDi
Rest - from 16 wks onwards
Not in 1st trimester
calculating EFW discordance dor DC twins using the formula
the largest-the smallest/the largest
if >25%:FGR -> FMU
if 20%: suspect SGR -> u/s weekly +umb A doppler
25% or 1 <10th centile
20% or 1 < 10th centile
When to deliver twin preg
MA: 32-34 (to avoid cord entanglement)
Tri: 35
MC: from 36
DC: 37
When to perform CX LENGTH SCAN IN TWIN
16-20w
What to do if Cx length less than 25 mm
200 mg progesterone vaginal once daily to 34 w
Remedies that has no role in CL <25 mm in twin preg.
- IM progesterone
- arabian pessary
- bed rest
- cx cerclage
- oral tocolytics