Infectious Diseases

Question 1

Treponema pallidum haemagglutination assay positive in a patient with a painless hard penile ulcer

Answer 1

Primary syphilis

Question 2

Are symptoms of fevers, night sweats and weight loss more indicative of primary TB or post-primary TB?

Answer 2

Post-primary TB

Question 3

What drug is used to treat falciparum malaria?

Answer 3

Quinine

Question 4

Pseudomembranous colitis caused by C. diff colonisation is treated with…

Answer 4

Metronidazole

Question 5

Common cause of outbreaks of childhood diarrhoea

Answer 5

Rotavirus

Question 6

Normal presentation is a prodromal phase of tingling or pain, followed by an eruption of a painful, blistering rash in a dermatomal distribution

Answer 6

Shingles

Question 7

Shingles, caused by a reactivation of VZV, can be treated early on with…

Answer 7

Acyclovir

(oral; or IV in immunocompromised patients)

Question 8

Painful vesicular rash over penis and testicles

What is the condition, and what can it be treated with?

Answer 8

Genital herpes

Acyclovir

Question 9

Purulent urethral discharge and dysuria

Answer 9

Gonorrhoea

Question 10

Used to treat primary syphilis

Answer 10

Procaine penicillin

(doxycycline or tetracycline can be used if penicillin is not tolerated)

Question 11

Most common type of viral hepatitis in the world

Answer 11

Hepatitis A

Question 12

Route of transmission for Hepatitis B and C

Answer 12

Intravenous / sexually transmitted

Question 13

Treatment of hepatitis A

Answer 13

Conservative management

Question 14

Pegylated interferon alpha plus ribavirin is a treatment for which hepatitis?

Answer 14

Hepatitis C

Question 15

Infectious mononucleosis is caused by which virus?

Answer 15

EBV

Question 16

Appropriate immediate management of patient presenting with bacterial meningitis

Answer 16

1.2g of IM benzylpenicillin

Question 17

Painful facial swelling, fever, lethargy, parotid swelling

Answer 17

Mumps

Question 18

Non-blanching, petechial rash in meningitis patient indicated it is caused by…

Answer 18

Neisseria meningitidis

Question 19

Patient travelling in South America for 3 months

Presents with lesion on forearm, showing an erythematous ulcer with a raised edge

Answer 19

Leishmaniasis

Question 20

Patient with history of fever, headache, malaise and dry cough

Patchy maculopapular rash (rose spots) and leukopenia

Answer 20

Typhoid / enteric fever

Question 21

Drug used in MRSA

Answer 21

Vancomycin

Question 22

Most common organism causing endocarditis

Answer 22

Streptococcus viridans

Question 23

Common cause of infective endocarditis in IV drug users and patients with prosthetic valves

Answer 23

Staphlococcus aureus

Question 24

Papular rash in the web spaces of fingers and toes, palms of hands, soles of feet, in the axilla and genitalia

Answer 24

Scabies

Question 25

Most common cause of septic arthritis in young fit adults

Answer 25

Gonococcal arthritis (e.g. *neiserriae gonnorrheae*)

Question 26

Most common cause of septic arthritis in older patients

Answer 26

*Staphylococcus aureus*

Question 27

Organism causing dysphagia and retrosternal discomfort in an HIV patient

Answer 27

*Candida albicans*

Question 28

Organism associated with Kaposi's sarcoma

Answer 28

Human herpes virus type 8 (HHV-8)

Question 29

HIV patient with encephalitis Multiple ring enhancing lesions on CT

Answer 29

Toxoplasmosis

Question 30

What can a Paul Bunnell test diagnose?

Answer 30

Infectious mononucleosis (due to EBV infection)