Infectious diseases & dermatology

Question 1

Most common form of extra pulmonary TB

Answer 1

Lymphatic

Question 2

Mainstay of treatment for Kawasaki disease

Answer 2

Immunoglobulin and aspirin

Question 3

Criteria for antiviral drugs for flu

Answer 3

Start within 48hrs of symptoms
65+ / < 6months / pregnant

or a b/g of….

Asplenism
Immunocompromised
IHD
CKD
Chronic liver disease
Chronic respiratory disease
Chronic neurological condition
Morbid obesity

Question 3

Infection of unclear cause in a child <3 months, what should be given alongside 3rd gen cef ? and why?

Answer 3

Amox for listeria

Question 4

School exclusion advice for mumps

Answer 4

return 5 days after onset of swelling

Question 5

Treatment of choice for severe Falciparum malaria

Answer 5

IV Artesunate

Question 6

Tx of choice for uncomplicated Falciparum malaria

Answer 6

Arteminisin combination therapy

Artemether + lumefantrine

Question 7

School exclusion for scarlet fever

Answer 7

Can go back 24hrs after treatment commenced

Question 8

What complication of chicken pox are pregnant women especially at risk of ?

Answer 8

Pneumonia

Question 9

Where does the rubella rash typically start

Answer 9

Behind the ears

Question 10

Rubella exclusion period

Answer 10

5 days from rash onset

Question 11

Differentiator between malaria and dengue fever

Answer 11

Rash

Question 12

Treatment for lyme disease, either rash present or +ve serology

2nd line

Answer 12

Doxy

Amox (1st line in pregnancy)

Question 13

Most common cause for bilateral facial palsy

Answer 13

Lyme disease

Question 14

When does gas gangrene develop

Answer 14

Deep soil wound

Question 15

antiviral drug in influenza criteria

Answer 15

Present with 48hrs of symptoms and any of the following

Pregnant (up to 2 weeks PP)
65+
<6 MONTHS
Or major chronic conditions

(Zanavir can be started 36hrs after sx in children)

Question 16

Most commonly used assay tests for HIV

Answer 16

p24

Question 17

Cat scratch disease

Answer 17

Bartonella henselae

Question 18

Organism causing chancroid

Answer 18

fastidious Gram-negative bacteria Haemophilus ducreyi.

Question 19

Treatment for chancroid

Answer 19

Azithromycin or ceftriaxone

Question 20

Onchocerciasis

Answer 20

Parasitic disease caused by the filarial nematode Onchocerca volvulus

Transmitted through black flies

Lots of skin reactions, ocular involvement (river blindness)

Question 21

CD4 count diagnostic of advanced HIV disease

anti-retroviral therapy should be considered

Answer 21

<200 mm3

<350 mm3

Question 22

Tape worm treatment

Answer 22

niclosamide or praziquantel

Question 23

Rose spots are seen in?

Answer 23

Typhoid, usually on the body

Question 24

Horder’s spots can present as part of what infection?

Answer 24

Psittacosis zoonotic infection caused by Chlamydia psittica Horders spots are found on the face

Question 25

Erythema marginatum

Answer 25

pale red maculopapular rash seen in rheumatic fever

Question 26

Causes of acanthosis nigricans

Answer 26

Malignancy, e.g. gastric carcinoma, lymphoma Acromegaly Cushing’s syndrome Diabetes Mellitus Polycystic ovarian syndrome Obesity

Question 27

Slapped cheek syndrome is also known as (2)

Answer 27

5th disease or erythema infectiosum

Question 28

Slapped cheek syndrome is caused by?

Answer 28

Parovirus B19

Question 29

Erythroderma definition

Answer 29

erythema affecting more than 90% of the body surface

Question 30

Exfoliative erythroderma is also known as Defined by

Answer 30

Red man syndrome Erythema affecting more than 90% of the body surface + exfoliation

Question 31

Most common underlying cause for exfoliative erythroderma

Answer 31

Atopic dermatitis

Question 32

Infected eczema first line abx Pen allergic

Answer 32

Flucloxacillin Erythromycin

Question 33

Pemphigus vulgaris vs Bullous pemphigoid Nikolsky sign

Answer 33

Middle aged vs elderly Flaccid lesions vs tense Fluids vs haemorrhagic blisters Oral involvement common vs rare Puritis rare vs common Positive vs negative

Question 34

Skin biopsy in Pemphigus vulgaris

Answer 34

Intra-epidermal deposition of IgG between cells throughout the epidermis

Question 35

Skin biopsy in Bullous pemphigoid

Answer 35

A band of IgG and/or C3 at the dermo-epidermal junction

Question 36

Antiviral treatment in chicken pox, what is the indications?

Answer 36

In immunocompromised patients and those at special risk (e.g. because of severe cardiovascular or respiratory disease or chronic skin disorder);

Question 37

Erysipelas is an infection of the superficial epidermis, most frequently caused by

Answer 37

Strep pyogenes

Question 38

Acne conglobata =

Answer 38

very severe form of acne where acne nodules track together and form sinuses

Question 39

Acne fulminans =

Answer 39

sudden severe inflammatory reaction that precipitates deep ulcerations and erosions, sometimes with systemic effects

Question 40

Pork tape worm species Beef tapeworm

Answer 40

Taenia solium Taenia saginata

Question 41

Haemoglobinuria and renal failure following treatment for malaria is suggestive of

Answer 41

Blackwater fever, which is caused by Plasmodium falciparum.

Question 42

Malaria is usually diagnosed using the...

Answer 42

Indirect Fluorescence Antibody Test (IFAT).

Question 43

The benign malarias are: And usually treated with...

Answer 43

P.vivax, P. malariae and P.ovale Chloroquine A course of primaquine is also required in P.vivax and P.ovale infection.

Question 44

Notifiable disease, time frame to notify Urgent Non urgent

Answer 44

24hrs 72hrs

Question 45

The median incubation period from HIV infection until the development of advanced HIV disease

Answer 45

10yrs

Question 46

Needlestick injury The risk of contracting Hepatitis C from a Hepatitis C positive source patient is The risk of contracting HIV from an HIV positive source patient

Answer 46

3-10% 0.2-0.5%

Question 47

In the UK, most cases of meningococcal septicaemia are caused by

Answer 47

Neisseria meningitidis group B

Question 48

Cysticercosis

Answer 48

An infection caused by the larvae of the parasite Taenia solium Whereby larval cysts infiltrate and disseminate throughout the lung, liver, eye, or brain.

Question 49

Differentiate dengue fever vs malaria

Answer 49

Rash

Question 50

Answer 50

Cutaneous vasculitis

Question 51

Hereditary angioedema is caused by

Answer 51

deficiency of C1 esterase inhibitor

Question 52

Appropriate test for whooping cough in patients of all ages with cough <2 weeks

Answer 52

Nasopharangeal swab / aspirate

Question 53

Appropriate test for whooping cough in patients of all ages with cough <3 weeks

Answer 53

PCR testing for pertussis toxcin (nasopharyngeal or throat swab).

Question 54

Appropriate test for whooping cough in with cough >2 weeks: 17+ 5-16 y/o

Answer 54

Antipertussis toxin IgG (serum) Antipertussis toxin IgG (oral fluid)