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NAPLEX 2022 > Infectious Diseases - PART 3 > Flashcards

Infectious Diseases - PART 3 Flashcards

(54 cards)

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1
Q

DAPTOMYCIN COVERAGE

A

MOST GP BACTERIA (MRSA, VRE)
NO GN ACTIVITY

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2
Q

WHEN SHOULD YOU NOT USE DAPTOMYCIN

A

PNEUMONIA
INACTIVATED BY LUNG SURFACTANT

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3
Q

DAPTOMYCIN INDICATIONS

A

SSTI
STAPH BLOODSTREAM INFECTIONS (MRSA)
ENDOCARDITIS

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4
Q

DAPTOMYCIN WARNING

A

MYOPATHY AND RHABDOMYOLYSIS
FALSE ↑ PT/INR

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5
Q

LINEZOLID COVERAGE

A

MRSA AND VRE

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6
Q

LINEZOLID RENAL DOSE ADJUSTMENT?

A

NOT NEEDED

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7
Q

LINEZOLID BIOAVAILABILITY

A

IV:PO 1:1

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8
Q

LINEZOLID CONTRAINDICATION

A

DO NOT USE WITHIN 2 WEEKS OF MAOI

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9
Q

LINEZOLID WARNING

A

DURATION RELATED MYELOSUPPRESSION (THROMBOCYTOPENIA)
OPTIC NEUROPATHY
SEROTONIN SYNDROME
HYPOGLYCEMIA

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10
Q

LINEZOLID SUSPENSION. ADMINISTRATION

A

DO NOT SHAKE

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11
Q

QUINUPRISTIN/DALFOPRISTIN SIDE EFFECTS

A

ARTHRALGIAS/MYALGIAS
INFUSION REACTIONS
HYPERBILIRUBINEMIA

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12
Q

QUINUPRISTIN/DALFOPRISTIN ADMINISTRATION

A

DILUTE WITH D5W ONLY
ADMINISTER VIA CENTRAL LINE ONLY

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13
Q

TIGECYCLINE COVERAGE

A

BROAD SPECTRUM GP (MRSA, VRE)
GN BACTERIA, ANAEROBES, ATYPICAL

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14
Q

QUINUPRISTIN/DALFOPRISTIN COVERAGE

A

MRSA
VRE (BUT NOT E.FAECALIS)

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15
Q

QUINUPRISTIN/DALFOPRISTIN IS NOT WELL TOLERATED, SO ONLY USED FOR THIS INFECTION

A

VRE E.FAECIUM INFECTIONS

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16
Q

TIGECYCLINE DOES NOT HAVE COVERAGE TO

A

3 P’S
PSEUDOMONAS
PROTEUS
PROVIDENCIA

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17
Q

TIGECYCLINE HAS LIMITED USES
WHAT ARE THE INDICATIONS?

A

COMPLICATED SSTI
INTRA-AB INFECTION
CA-PNEUMONIA

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18
Q

TIGECYCLINE BOXED WARNING

A

↑ RISK OF DEATH
ONLY USE WHEN NECESSARY

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19
Q

DO NOT USE TIGECYCLINE FOR THSES INFECTIONS

A

BLOODSTREAM INFECTIONS
DOES NOT ACHIEVE ADEQUATE CONCENTRATIONS

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20
Q

WHAT COLOR SHOULD TIGECYCLINE BE WHEN RECONSTITUTED

A

YELLOW-ORANGE COLOR

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21
Q

POLYMIXINS ARE PRIMARILY USED FOR

A

MDR GRAM NEGATIVE PATHOGENS

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22
Q

POLYMIXIN WARNING

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A

NEPHROTOXICITY
NEUROTOXICITY THAT CAN LEAD TO RESPIRATORY PARALYSIS

23
Q

CHLORAMPHENICOL BOXED WARNING

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A

SERIOUS AND FATAL BLOOD DYSCARIAS

24
Q

CHLORAMPHENICOL WARNING

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A

GRAY SYNDROME WITH HIGH SERUM LEVELS: CIRUCULATORY COLLAPSE, CYANOSIS, ACIDOSIS,COMA, DEATH

25
CLINDAMYCIN COVERAGE
MOST GP BACTERIA (SOME CA-MRSA) ANAEROBES NO GN COVERAGE
26
CLINDAMYCIN RENAL DOSE ADJUSTMENT NEEDED?
NOT NEEDED
27
CLINDAMYCIN BOXED WARNING
COLITIS (C.DIFF)
28
WHAT TEST SHOULD BE PERFORMED PRIOR TO USING CLINDAMYCIN ON S.AUREUS?
INDUCTION TEST (D-TEST) TEST IF BUG WILL INDUCE RESISTANCE
29
CLINDAMYCIN COMMON USE
PURULENT AND NON-PURULENT SKIN INFECTIONS DENTAL ABSCESSES (BETA LACTAM ALTERNATIVE)
30
METRONIDAZOLE COVERAGE
ANAEROBES AND PROTOZOAL INFECTIONS
31
METRONIDAZOLE IS EFFECTIVE IN THESE INFECTIONS
BACTERIAL VAGINOSIS TRICHOMONIASIS IN COMBO FOR INTRA-AB INFECTIONS
32
METRONIDAZOLE BIOAVAILABILITY
IV:PO 1:1
33
METRONIDAZOLE CONTRAINDICATIONS
PREGNANCY 1ST TRIMESTER ALCOHOL OR PROPYLENE GLYCOL CONTAINING PRODUCTS DURING OR WITHIN 3 DAYS OF TREATMENT D/C
34
FIDAXOMIXIN IS ONLY INDICATED FOR
C.DIFF NOT EFFECTIVE FOR SYSTEMIC INFECTIONS
35
RIFAXIMIN HAS 4 MAIN INDICATIONS
TRAVELER'S DIARRHEA ↓ RECURRENCE OF HEPATIC ENCEPHALOPATHY IBS-D C.DIFF (OFF-LABEL)
36
RIFAXIMIN BIOAVAILABILITY
<1% ABSORPTION NOT EFFECTIVE FOR SYSTEMIC INFECTIONS
37
FOSFOMYCIN COVERAGE
E.COLI (INCLUDING ESBL) F.FAECALIS (INCLUDING VRE)
38
FOSFOMYCIN INDICATION AND DOSING
SINGLE DOSE REGIMEN FOR UNCOMPLICATED UTI
39
FOSFOMYCIN PACKET GRANULES CONTAIN HOW MANY GRAMS
3 GRAMS PER PACKET
40
NITROFURANTOIN USE
UTI (CYSTITIS ONLY)
41
NITROFURANTOIN COVERAGE
E.COLI KLEBSIELLA ENTEROBACTER S.AUREUS ENTEROCOCCUS (VRE)
42
WHAT IS THE DRUG OF CHOICE FOR UNCOMPLICATED UTI
NITROFURANTOIN
43
MICROBID VS MICRODANTIN
MACROBID IS BID DOSING MACRODANTIN IS QID DOSING
44
MACROBID DOSING FOR UNCOMPLICATED UTI
100 MG BID X 5 DAYS
45
NITROFURANTOIN CONTRAINDICATIONS
RENAL IMPAIRMENT < 60
46
NITROFURANTOIN WARNING
HEMOLYTIC ANEMIA IN G6PD DEFICIENCY
47
RIFAMPIN SIDE EFFECTS
↑ LFTS HEMOLYTIC ANEMIA (POSITIVE COMMBS TEST) FLU LIKE SX ORANGE-RED DISCOLORATION OF SECRETIONS
48
ISONIAZID: WHAT VITAMIN SHOULD BE TAKEN WITH THIS AGENT AND WHY?
PYRIDOXINE (VITAMIN B6) TO ↓ RISK OF INH-ASSOCIATED PRIPPHERAL NEUROPATHY
49
ISONIAZID BOXED WARNING
HEPATITIS
50
ISONIAZID WARNING
PERIPHERAL NEUROPATHY (RECOMMENDED TO TAKE PYRIDOXINE AS SUPPLEMENTAL)
51
ISONIAZID SIDE EFFECTS
↑ LFTS DILE HEMOLYTIC ANEMIA
52
PYRAZINAMIDE WARNING
ACUTE GOUT CAUSED BY HYPERURICEMIA/GOUT
53
ETHAMBUTOL WARNINGS
OPTIC NEURITIS CONFUSION AND HALLUCINATIONS
54
PHENAZOPYRIDINE

NAPLEX 2022 (37 decks)

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