Infectious Esophagitis

Question 1

What is the most common microbe responsible for infectious esophagitis?

Answer 1

Candidia Albicans

Question 2

How to diagnose infectious esophagitis

Answer 2

EGD

Question 3

S/s of infectious esophagitis

Answer 3

Odynophagia and dysphasia, oral thrush

Question 4

Treatment plan for candida infectious esophagitis

Answer 4

Oral fluconazole 200-400mg x1 then 100-200mg po QD x14-21 days

Question 5

Refractory infectious esophagitis treatment

Answer 5

Voriconazole 200mg BID x14 then daily x7 days after symptoms disappear
Can do micafungin if unable to swallow

Question 6

S/s of herpetic infectious esophagitis

Answer 6

Vesicles on the nose and lips

Question 7

What is the diagnostics for herpetic infectious esophagitis

Answer 7

EGD: vesicles and small punched out ulcerations, biopsies w/ ground glass nuclei, eosinophilic Cowdry’s type A inclusion bodies, and giant cells

Question 8

Treatment plan for herpetic infectious esophagitis

Answer 8

Immunocompetent: Acyclovir 200mg 5x qd x 7-10days
Immunocompromised: Acyclovir 400mg 5x qd 14-21 days
Alternative therapies: Famciclovir 500mg po TID or Valcyclovir 1g po TID
Or Acyclovir IV for severe cases

Question 9

What is the diagnostic for CMV infectious esophagitis

Answer 9

EGD: serpiginous ulcers

Question 10

Tx plan for CMV esophagitis

Answer 10

Ganciclovir and Valganciclovir for 3-6 weeks until healed and may need maintenance therapy

Question 11

S/s of Infectious esophagitis

Answer 11

Odynophagia: most common
Dysphasia
Chest pain
Hemorrhage