Infectious Mononucleosis Flashcards Preview

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Flashcards in Infectious Mononucleosis Deck (6)
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1
Q

How does Mono present?

A
Fatigue - Malaise - Fever/Chills - Aches
Headache
Fine red skin rash
Loss of apetite
Cough
Nausea

Lymphadenopathy - Swollen red/white tonsils - Splenomegaly - Periorbital & Pharyngeal Oedema

2
Q

What causes mono?

A

Epstein Barr Virus (EBV)

3
Q

How do we investigate Glandular fever?

A

Serology for antibodies (IgM current and IgG past)
Blood Film: Atypical mononuclear lymphocytes (<20% of them)
Monospot Test: Heteophile Antibody Test

4
Q

Why isnt the monospot test reliable?

A

Its only 70-90% sensitive
Also shows false positives for many conditions e.g:
SLE, lymphoma, pancreatic cancer, leukeamia, secondary syphilis, rubella, malaria & hepatitis

5
Q

How is Mono treated?

A

Rest!!!

Corticosteroids if pharyngeal oedema constricts airway

Avoid penicillin esters just like tonsilitis. e.g. amoxicillin, co-amoxiclav & ampicillin as they react with EBV -> Rash

6
Q

How does Mono spread?

A

By kissing (sharing pharyngeal secretions)