Pulmonary Hypertension Flashcards Preview

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Flashcards in Pulmonary Hypertension Deck (7)
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1
Q

Define PHT?

A

A mean pulmonart arterial pressure > 25mmHg at rest

2
Q

What are the causes for PHT?

A
Idiopathic
Left Heart Disease (e.g. Mitral Regurg)
Chronic Pulmonary Disease
Chronic Thromboembolic PH (CTEPH)
HIV -- Congenital L-R Shunt -- Collagen Vascular Disease -- Portal Hypertension\
3
Q

What are the symptoms of PHT?

A

Exertional Dyspnoea and Syncope

Chest Tightness

4
Q

What aer the signs of PHT?

A
Raised JVP
RV Heave
Hepatomegaly
Loud pulmonary heart sound
Ankle Oedema
5
Q

What are the tests for PHT?

A
ECG
CXR
CT Pulmonary Angiogram
Echocardiogram
V/Q Scan
Lung Function Tests
Right Heart Catherterisation:
 - Pulmonary Arterial Pressure
 - Pulmonary Wedge Pressure
 - Cardiac Output
6
Q

How do we treat PHT?

A

Treat the underlyin cause

O2 - Anticoagulants - Diuretics - Vasodilating CCBs

Targeted vasodilators:
Phosphodiesterase Inhibitors e.g. sidenafil - Phosphodiesterase is a vasoconstricter
Prostacyclin - Vasodilator type of prostoglandin
Endothelin Receptor Antagonist e.g. Bosentan - Targets an excess endothelin (natural vasoconstrictor)

Lung/Heart Transplant
Thromboendarterectomy

7
Q

What does PHT lead to?

A

Right heart hypertrophy and Cor Pulmonale