Inflammation Flashcards

1
Q

What is inflammation

A
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2
Q

What are cardinal signs of inflammation

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3
Q

What are the 5R’s inflammatory steps?

A
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4
Q

What is histamine synthesised from and metabolised by?

A
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5
Q

What is histamine released by and what inhibits it?

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6
Q

What are the 4 types of histamine receptors?

A
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7
Q

What are the effects of stimulation of H1 and H2 receptors?

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8
Q

What are histamines 2 pathological roles?

A
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9
Q

Describe the triple response

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10
Q

What is histmaines role in gastric acid secretion

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11
Q

What are the therapeutic and side effects of H1 antagonists?

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12
Q

What are the therapeutic and side effects of H2 antagonists?

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13
Q

What are the functions of bradykinin?

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14
Q

What are the pharmacological effects of bradykinin?

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15
Q

Synthesis and metabolism of bradykinase?

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16
Q

Distribution of 5-HT?

A
17
Q

What are the inflammatory actions of 5-HT?

A
18
Q

Define

A
19
Q

Why are eicosanoids important?

A
20
Q

Formation of prostanoids?

A
21
Q

What are cycloxygenases and what is it attached to

A
22
Q

What are the differences between COX-1, COX-2 and COX-3?

A
23
Q

What are some classical prostaglandins?

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24
Q

Actions of eicosanoids

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25
Q

Effects of the mediators on bronchospasm?

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26
Q
A