Inflammation Flashcards
(33 cards)
Anaerobic
lack of oxygen
apoptosis
Cell death, body getting rid of abnormal cells
endogenous
internal cause of origin
exogenous
external factors
Lysosomal
Cells that break down excess cell parts and help to facilitate apoptosis
proptosis
cell death triggered by inflammation. Examples include reduced ATP, PH and cell membrane damage.
Hypertrophy
Enlargement of cell size, such as myocarditis. Inflammation of heart from working too hard.
hyperplasia
increase in the number of cells
Metaplasia
Mature cell is replaced.
sequelae
unwanted outcomes from a condition.
dysplasia
varying tissue cell shapes.
anaplasia
cells that are undifferentiated with variable nuclear and cell structors.
Three lines of defence in inflammation
1) mechanical barrier such as tears, mucus.
2) Phagocytosis: cells engulf and destroy bacteria
3) antibody production.
Inflammatory steps
-Bradykinin released from injured cell which activates pain receptions.
-mast cells and basophils release histamines.
-capillary dilation occurs, which causes increase in blood flow permeability, plasma proteins then move into interstitial fluid.
leukocytes migrate
chemotaxis
cell migration in response to concentration of extracellular fluid
angiogenesis
new blood vessel formation
diapedesis
blood cells pass through intact walls of capillaries during inflammation
granuloma
clustered immune cells
hematopoiesis
red bone marrow produces blood cells.
hemtocrit
% of red blood cells in blood
Capillary exchange
transfer of material from blood to tissues in capillaries, by diffusion.
Histamine
mast cells cause vasodilation and increase capillary permeability.
Platelet activating factor
cell membrane of platelets activates neutrophils
cytokines
T lymphocytes and macrophages induce fever.
