Inflammation and Healing 2

Question 1

Name 3 phases of wound healing

Answer 1

1. Inflammation
2. Proliferation
   - wound contraction (start to lay down new tissue)
3. Remodeling
   - Closing of the wound, scar tissue forms

Question 2

Difference between 1st and 2nd intention healing

Answer 2

1st intention healing: clear, clean margins (surgery)

2nd intention healing: irregular margins, delayed healing (ulcer, burn, etc)

Question 3

Describe 4 stages of pressure ulcers

Answer 3

1. Intact skin (inflammed, itchy)
2. Partial thickness skin loss (blister)
3. Full thickness skin loss (necrosis of fat layers)
4. Necrosis of fascia, muscle, bone; tunneling, undermining

Question 4

What cell helps contract wound edges?

Answer 4

Myofibroblasts

Question 5

What cell forms granulation tissue?

Answer 5

Angioblasts

Question 6

What cell is responsible for bone growth?

Answer 6

Osteoblasts

Question 7

What cell is responsible for bone breakdown?

Answer 7

Osteoclasts

Question 8

Dehiscence

Answer 8

Reopening of surgical wound

Question 9

What are trabeculae?

Answer 9

Matrix of collagen that makes of porous, spongy bone. Gives bone strength and decreases weight