Inflammation and Tissue Repair Flashcards Preview

DPT 6120 > Inflammation and Tissue Repair > Flashcards

Flashcards in Inflammation and Tissue Repair Deck (12)
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1
Q

Inflammation Phase

A

prepares wound for healing

Days 1-6

2
Q

Proliferation Phase

A

rebuilds damaged structures and strengthens the wound

Days 3-20

3
Q

Maturation Phase

A

Modifies the scar tissue into its mature form

Day 9 onward

4
Q

Factors that affect the healing process

A

Local factors
External Forces
Systemic factors

5
Q

What are the determinants of healing?

A

Regenerative capacity of the tissue, vascular supply, extent of damage

6
Q

Cartilage

A
  • Limited ability to heal
  • Lacks lymphatics, blood vessels, and nerves
  • Cartilaginous injuries that also involve subchondral bone allow inflammatory cells from bone to gain access to repair the injured cartilage
7
Q

Tendons and Ligaments

A
  • The potential for repair of these tissues depends on the type of tendon or ligament, extent of damage, vascular supply, and control of movement
  • If healing occurs, tendons possess a unique scar maturation phase that can achieve an advances state of repair
  • Ligaments heal better with controlled passive mobilization
8
Q

Skeletal Muscle

A
  • Can be injured by trauma, strain, or muscle diseases
  • Healing can occur in some cases through stem cells that can proliferate and differentiate
  • After severs contusions, a calcified hematoma (localized collection of blood outside the blood vessels) may develop- myositis ossificans ( formation of bone tissue inside muscle tissue after a traumatic injury to the area) is a rare complication
9
Q

4 Stages of healing for bone: Inflammation

A

Inflammation (begins shortly after impact) - creates hematoma, disrupts blood supply, lowers pH

10
Q

4 Stages of healing of bone: Soft Callus

A

Soft Callus (beings after swelling subsides) - stabilizes fracture, decreases pain, and reduces chance of fat embolism

11
Q

4 States of healing of bone: Hard Callus

A

Hard Callus (3 weeks to 4 months)- Corresponds to clinical healing period

12
Q

4 Stages of healing a bone: Bone remodeling

A

Bone remodeling (takes months to years)- Healed fibrous bone is converted to lamellar bone, and medullary canal becomes patent again