Influenza and Covid Flashcards
(9 cards)
Which is the most important type of Influenza?
Influenza A
How many DNA strands does Influenza A viruses have?
8
What is hemagglutanin (HA) and what does it do?
A surface protein on Influenza viruses which binds to the receptor on the cell surface
What is the receptor used by Influenza virus to enter the cell?
Sialic acid residues
What is neuraminidase (NA) and what does it do?
A surface protein on the Influenza viruses which cleaves the virus of the host cell membrane so it can be released
Where does replication of the influenza genome take place in the cell?
Nucleus
How does influenza viruses change?
Genetic drift and shift
How come coronaviruses can have such a large genome?
Its polymerase has a simple form of proofreading with 3’->5’ exonuclease activity
How does the coronaviruses enter the cell?
With the spike protein, which needs to be activated by cellular proteases to activate the virus. Use big range of receptors