Inheritance, Variation and Evolution Flashcards
(72 cards)
What is variation?
All the differences in the characteristics of individuals in a population
What are the causes of variation?
- Genetic causes
- Environmental causes
- Combination of genes and environment
What are the genetic causes of variation?
Alleles inherited from parents
Give an example of genetic variation:
- hair colour
- eye colour
Give an example of environmental variation:
- Colour of flowers depending on pH of soil
- Language in humans
Give an example of combination of genes and environment:
Height in humans
What is genetic variation caused by?
Genetic variation in a population is due to mutations
What are genetic mutations?
Changes to DNA
What is DNA?
deoxyribonucleic acid - it is the chemical that all genetic material in a cell is made from. It contains coded information for the cell.
What is a chromosome?
The structure made of DNA that codes for all the characteristics of an organism.
What is the structure of DNA?
DNA is a polymer made up of two strands forming a double helix. The DNA is contained in structures called chromosomes.
What is a gene?
A gene is a small section of DNA on a chromosome. Each gene codes for a particular sequence of amino acids, to make a specific protein.
What is a genome?
Genome refers to the entire set of genetic material in an organism. The whole human genome has now been studied and this will have great importance for medicine in the future.
Describe the nucleotide structure:
Every nucleotide is made of one sugar molecule, one phosphate molecule and one base.
What is the sugar-phosphate backbone?
The sugar and phosphate molecules in the nucleotide form a backbone to the DNA strands. The sugar and phosphate molecules alternate. One of four different bases (A,T,C,G)
How do the bases pair together?
A always pairs up with T, and C always pairs to G. The order of bases in a gene determines the order of amino acids in a protein. In the complementary strands a C is always linked to a G on the opposite strand and a T to an A.
How are amino acids formed?
Each amino acid is coded for by a sequence of three bases in a gene. The amino acids are joined together to make various proteins, depending on the order of the gene’s bases.
Does all DNA code for proteins?
No - there are parts of DNA that do not code for proteins. Some of these non-coding parts switch genes on and off, so they control whether or not a gene is expressed (if it is used to make a protein)
What is protein-synthesis?
1) Proteins are made in the cell cytoplasm on tiny structures called ribosomes
2) To make proteins, ribosomes use the code in the DNA. DNA is found in the cell nucleus and can’t move out of it as it is too big. So the cell needs to get the code from the DNA to the ribosome.
3) This is done using a molecule called mRNA - made by copying the code from DNA. The mRNA acts as a messenger between the DNA and the ribosome (carries it between the two)
4) The correct amino acids are brought to the ribosomes in the correct order by carrier molecules
Describe how a protein might be used?
When a chain of amino acids has been assembled, it folds into a unique shape which allows the protein to perform a task:
- Enzymes
- Hormones
- Structural proteins
Explain a mutation:
Mutations occur continuously. Mutations change the sequence of the DNA bases, producing a genetic variant (different form of gene). As the sequence of DNA bases codes for amino acids to make a protein, a mutation can change the protein produced.
What is mRNA?
mRNA - Messenger RNA is a linear molecule which carries a copy of the gene to be expressed from the nucleus. Every group of three bases (a ‘triplet’) is described as a codon because each one codes for an amino acid.
What is tRNA?
tRNA - Transfer RNA has a cloverleaf shape. It is made from a single strand of RNA which folds due to base pairing to form this unusual shape. It has a triplet anti-codon site and an attachment site for a specific amino acid.
what is rRNA?
rRNA - Ribosomal RNA and proteins form the ribosome. The ribosome is the structure where protein synthesis takes place.