Innate Immunity: Anatomical And Physical Barriers Flashcards

1
Q

What is the first line of defense called?

A

Innate immunity

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2
Q

Is innate immunity specific or non-specific?

A

Non-specific

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3
Q

What is the second line of defense called?

A

Adaptive immunity

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4
Q

Is adaptive immunity specific or-non-specific?

A

Specific

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5
Q

What are the 2 components of the immune systems?

A

Cellular and humoral

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6
Q

When do we develop innate immunity?

A

At birth

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7
Q

What is the 1st line of defense for innate immunity?

A

Skin, mucous membranes,chemicals

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8
Q

What is the 2nd line of defense for innate immunity?

A

Phagocytosis, complement, interferon, inflammation, fever

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9
Q

What is the mechanical factor of the respiratory tract?

A

Ciliary movement

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10
Q

What is the mechanical factor of the intestinal tract?

A

Peristaltic movement

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11
Q

What is the mechanical factor of the skin?

A

Self- cleansing, hair coat

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12
Q

What is the mechanical factor of washing done by?

A

Tears or saliva

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13
Q

Where does the mechanical factor of a dense mucus layer come from?

A

Vagina, digestive tract, respiratory tract

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14
Q

How do all mechanisms defend the body?

A

By mechanically removing infectious microorganisms and preventing entry

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15
Q

T/F: some of the innate mechanisms involved in the protection of the respiratory tract against infection and the influence of particle size on the size of deposition of particles within the respiratory tract

A

True

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16
Q

What is the sticky, viscous substance that coats epithelial cell layers and avoids microorganisms attachment?

A

Mucus

17
Q

What inhibits growth of bacteria?

A

Fatty acids?

18
Q

What is present in tears, saliva, secretions of nasal tract and inhibit the growth of infectious agents?

A

Lysozyme and phospholipase

19
Q

What component of sweat and gastric juices has antibacterial effects?

A

Low pH

20
Q

What is an example of a surfactant in lungs that enhances phagocytosis?

A

Opsonins

21
Q

What on the skin and digestive tract prevents infection by secreting inhibitory substances that inhibit colonization and growth of infectious microorganisms?

A

Normal biota

22
Q

What does the gastric mucosa secrete that has a pH of 2 or less?

A

HCl

23
Q

What does bile and the pancreas secrete?

A

Detergents

24
Q

The skin has sebaceous glands, what is the name of the water repellent and acidic secretion?

A

Sebum

25
Q

What are the positive charged proteins that insert into negative charged microbial membranes and punch holes into them?

A

Defensins and Cathelicidins

26
Q

What is found in milk and sequesters iron, making it unavailable for bacteria growth?

A

Lactoferrin

27
Q

What generates reactive oxygen compounds that damage microbes?

A

Lactoperoxidase

28
Q

What cells from the intestine of horses are filled with large eosinophilic granules and are the major source of intestinal defensins?

A

Paneth cells

29
Q

In healthy animals, do commensalism bacteria, present in digestive, respiratory, and reproductive tracts, produce disease?

A

No

30
Q

What type of bacteria compete with pathogens for nutrients and space?

A

Commensal bacteria

31
Q

What type of bacteria have an influence on the intestine development and the adaptive immune response?

A

Commensal bacteria

32
Q

What bacterial flora excludes pathogens from body surfaces by competition?

A

Normal bacterial flora