Innate Immunity - TLR

Question 1

TRL1:TRL2 ligand

Answer 1

lipopeptides and GPI

Question 2

TRL1:TRL2 microorganisms

Answer 2

Bacteria and parasites

Question 3

Cells carrying TLR1:TLR2

Answer 3

monocytes, DCs, eosinophils, basophils, and mast cells

Question 4

TLR2:TLR6 ligand

Answer 4

lipotichoic acid and zymosan

Question 5

TLR2:TLR6 microorganisms

Answer 5

Gram positive bacteria and yeast

Question 6

Cells carrying TLR2:TLR6

Answer 6

monocytes, dendritic cells, eosinophils, basophils, and mast cells

Question 7

TLR3 ligand

Answer 7

double stranded viral RNA

Question 8

TLR 3 microorganisms

Answer 8

Viruses (WNV)

Question 9

Cells carrying TLR3

Answer 9

NK cells

Question 10

TLR4:TLR4 ligand

Answer 10

lipopolysaccharide

Question 11

TLR4:TLR4 microorganisms

Answer 11

gram negative bacteria

Question 12

Cells carrying TLR4:TLR4

Answer 12

macrophages, DCs, mast cells, eosinophils

Question 13

TLR5 ligands

Answer 13

flagellin

Question 14

TLR5 microorganisms

Answer 14

motile bacteria w flagellum

Question 15

Cells carrying TLR5

Answer 15

intestinal epithelium

Question 16

TLR7 ligands

Answer 16

ss viral RNA

Question 17

TLR7 microorganisms

Answer 17

viruses (HIV)

Question 18

Cells carrying TLR7

Answer 18

plasmacytoid DCs, NK cells, eosinophils, and B cells

Question 19

TLR8 ligands

Answer 19

ss viral RNA

Question 20

TLR8 microorganisms

Answer 20

viruses (influenza)

Question 21

Cells carrying TLR8

Answer 21

NK cells

Question 22

TLR9 ligand

Answer 22

unmethylated CpG-rich domain

Question 23

TLR9 microorganisms

Answer 23

bacteria viruses (herpes)

Question 24

Cells carrying TLR9

Answer 24

plasmacytoid DCs, B cells, eosinophils, and basophils