Integ Basic Science PPT Flashcards
What is the largest organ in the body?
The Skin; covers 25 square feet
15% of BW
More patients suffer from chronic wounds than what other diseases combined?
Alzheimer’s, Parkinson’s and cancer
Five main functions of the skin:
- Temperature: more skin loss will effect the body temp and the ability to regulate it
- Touch: Sensory
- Lymphatics: Absorb 60% of what is put on your skin, skin has own respiratory system, tattoos dye lymph nodes
- Protection: UV and trauma
- Vitamin D: from the sun is absorbed
Five Layers of the Epidermis
superficial to deep: corneum, lucidum, granulosum, spinosum, basal
What are basal and spinosum layer often referred to together?
Stratum Malpighi
Stratum Corneum
Protective layer
Outermost layer and turned over 30 days
comprised of 15-20 layers of non-nucleated keratinized cells
Stratum Lucidum
Transparent layer found mostly in the soles of the feet and palm of the hands
transitional layer: 1-5 layers thick
Stratum Granulosum
1-5 cells thick
waterproof barier to prevent fluid loss
synthesizes keratonyaline (keratin precursor)
Stratum Spinosum:
Prickle Cell layer
has desmosomes which terminate in spiny projections
help protect skin from abrasion
LANGERHAN’S cells provide antigens to T-lymphocytes
Stratum Germanitivum
single cell layer
give germinal cells that are needed for regeneration of epidermis
has melanocytes which give skin pigment
Basement Membrane
epidermal-dermal junction where the cells are responsible for mitotic growth and epidermal regeneration (30 days)
Rete Ridges or Rete Pegs
downward fingerlike projections in the epidermis
meets with upward projections that connect to anchor the dermis to the epidermis, should move as one in a healthy person
At what age do the Rete Ridges flatten?
In your 60s, causing the anchoring between the epidermis and the dermis to be diminished giving a higher chance for epidermis to detach from dermis
tears the uppermost layers of the skin
Two layers of the Dermis
- Papillary layer: Anchors dermis to epidermis
2. Reticular Layer: dense, deep accessory organs such as epidermal appendages (hair follices, lymph vessels) Vascular
Functional Components of the dermis
hair follicles nerve ending lymph vessels capillaries collagen elastin sweat glands sebaceous glands (controls pH)
The purpose of subcutaneous tissue
adipose or fat
connective and elastic tissue: insulate, support, cushion, and store energy
Dermatologic Exam
OSAP not SOAP
Objective Subjective Assessment Plan Examine the patient and than take a detailed history
Use hands during an evaluation to feel for:
texture and consistency
assess for tenderness
flat or elevated
Blanching
when sitting we cross our legs, when we undo we have a red mark. If you push on the red mark it turns white and than back to red as the blood refills with capillary. This is blanching
Five places to make sure you dont forget to assess during an examination
- scalp
- mouth
- eyes
- nails
- hair
Primary Lesions
first to appear and their ID is the most important aspect of the dermatological physical examination
Secondary Lesions
are depressed and manifest below the plane of the skin
Flat (2)
macule/patch
Raised Smooth (4)
papule/plaque/cyst/nodule