Integrative Tissue Metabolism. Flashcards

1
Q

What is Adipose tissue made of?

A

Adipocytes (fat cells).

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2
Q

What is metabolic activity of Adipose Tissue?

A

Very metabolically active. 2nd to only Skeletal Muscle.

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3
Q

How does Adipose Tissue respond?

A

Through hormones.

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4
Q

What percentage mass of a young adult is Adipose tissue?

A

15%.

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5
Q

How is the energy of TAG released?

A

When hormones signal need for metabolic energy, the TAG’s are mobilised and transported to tissues.

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6
Q

What happens to the actual stuff in TAG for energy production?

A

Fatty acids are oxidised via BETA-oxidation to produce energy and Glycerol can be used for energy production or GNG.

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7
Q

At rest, what percentage of the energy can be attributed to skeletal muscle?

A

20%.

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8
Q

During active muscular work, what percentage of the energy can be attributed to skeletal muscle?

A

90%.

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9
Q

What can Skeletal Muscle use as energy?

A

EVERYTHING.

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10
Q

What is the energy source for skeletal muscle at rest?

A

Fatty acids from adipose. 80%.

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11
Q

What is the energy source for skeletal muscle at short bursts of energy?

A

Creatine Phosphate.

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12
Q

What is short burst?

A

First few minutes.

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13
Q

What enzymes the synthesis of creatine phosphate?

A

Creatine phosphokinase.

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14
Q

What is the energy source for skeletal muscle at moderately active?

A

Glucose from it’s own glycogen stores and Liver’s stores and fatty acids and ketones.

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15
Q

What is the energy source for skeletal muscle at extremely active?

A

Muscle glycogen –> Lactate. Cori cycle also occurs in liver where the lactate will be converted to glucose.

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16
Q

What is the energy source for skeletal muscle at starvation?

A

Ketosis or protein breakdown.

17
Q

Rate of metabolism for cardiac muscle?

A

High metabolism, continually active.

18
Q

What lipid and glycogen stores does cardiac muscle have?

A

Not much.

19
Q

What is the primary fuel for heart muscle?

A

Fatty acids.

20
Q

What type of respiration does the heart muscle undergo?

A

Aerobic.

21
Q

What other fuels can the cardiac muscle use?

A

Glucose and ketones.

22
Q

What fuel reserves does brain muscle have?

A

None.

23
Q

What is the primary fuel source?

A

Glucose from diet or liver.

24
Q

What does brain use in fasting conditions?

A

Ketones. They can cross blood barrier.

25
Q

Can brain use fatty acids?

A

No. They cannot cross Blood-brain-barrier.

26
Q

What respiration to RBC’s do?

A

Anaerobic.

27
Q

What cell has the highest rate of glucose utilisation in the body?

A

RBC’s.

28
Q

What is RBS’s fuel source?

A

Glucose.