integument Flashcards

0
Q

basale layer of epidermis

A

Stratum Germinativum

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1
Q

Cells occupying the Stratum Germinativum

A

Melanocytes, Langerhans, Merkel

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2
Q

purpose of melanin

A

protects DNA of germinal cells of stratum gerinativum

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3
Q

function of Langerhans cells

A

antigen presentation - they migrate through the dermis to lymph nodes and interact with helper T cells

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4
Q

the layers of the epidermis from bottom to top

A

germinativum, spinosum, granulosum, lucidum, corneum

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5
Q

what cell type is partcular to the spinosum

A

prickle cells anchored to one another by tonofilaments making tonofibrils called prekeratin. Prickle cells distribute tesile stress.

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6
Q

function of Merkel cell

A

paracrine mechanorececptors. may migrate up to spinosum. associate with free nerve endings of cutaneous sensory receptors

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7
Q

keratohyalin

A

soft keratin mixed with a few other proteins that cause the granulosum to stain basophilic

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8
Q

which layer is only predominant in thick skin

A

lucidum.

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9
Q

cells that occupy lucidum

A

dead keratinocytes filled with keratin filaments and a few organelles

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10
Q

Psoriasis

A

extreme turn over of keratinocytes (a week) do not allow cohesive corneum layer

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11
Q

what layer is most noticeable in thick skin

A

corneum

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12
Q

what is the specific tissue of dermis

A

dense irregular CT

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13
Q

Rete pegs

A

epidermal reaching into the dermis

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14
Q

Papillae

A

dermis projections into the epidermis

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15
Q

3 components of the DE Junction

A

hemidesmosomes, basalamina, CT fibers (collagen type 1)

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16
Q

2 layers of the dermis

A

papillary loose CT (more collagen type 3, capillary loops), reticular dermis dense irregular CT (more collagen type 1, capillary and nerve networks)

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17
Q

the plexuses from bottom to top

A

subcutaneous, cutaneous, subpapillary

18
Q

what type of specific tissue is the hypodermis (AKA superficial fascia)

A

adipose

19
Q

to what layers do hair follicles descend

A

the dermis and hypodermis

21
Q

layers of a hair follicle from the outside to inside

A

CT sheath, external root sheath, internal root sheath, shaft (cuticle, cortex, medulla)

21
Q

which parts of a hair contain which types of keratin

A

from the inside out: medulla is soft, cortex is hard, internal root sheath is soft

22
Q

how long are the growing and resting phases of hair follicles

A

growth phase 2-6 years, resting phase 2-6 months

23
Q

myoepitheilium

A

epithelial cells with contractile properties that surround the secretory portion of sweat glands. a thick basement membrane lies beneath.

24
Q

entire cell is secreted

A

holocrine (sebaceuous)

25
Q

muscle that makes hair stand on end and squeezes the sebaceous gland

A

arrector pilli

26
Q

the only skin appendage in thick skin

A

eccrine sweat gland

27
Q

secretions are made via exocytosis

A

merocrine (eccrine, apocrine)

28
Q

4 cell types of eccrine glands

A

low columnar clear cells (water, salts), low columnar dark cells (glycoprotein), myoepithelium, stratified cuboidal duct cells

29
Q

eponychium

A

the cuticle (superior to the nail groove)

30
Q

how do apocrine glands differ from eccrine glands (3 reasons)

A
  1. they are found only in specific body regions 2.open onto the hair follicle
  2. wider lumens
32
Q

pacinian (patchinian) corpuscles

A

DEEP pressure unmyelinated nerve of thick skin; Ct capsule around onionbulb modified Schwann capsules (perineural epithelium) around the terminals in the dermis, hypodermis (subcutaneuous)

33
Q

which layer of the epidermis contains keratohyaline?

A

stratum granulosa

34
Q

Meissner’s corpuscles

A

SENSITIVE mechanoreceptors found in dermal papilla of thick skin encapsulated by CT. contain several axon terminals and stacks of modified Schwann cells

35
Q

3 layers lining hair follicle

A

conn tissue sheath, external root sheath (epitheilium of hair follicle) , internal root sheath (soft keratin proximal to the hair)

35
Q

nerve structure in Meissner’s

A

2 to 9 myelinated fibers enter at the base and sides, branch repeatedly and terminate on the receptor cells

36
Q

where does one find connective tissue papilla?

A

base of hair root just below the MATRIX, dermal region

38
Q

Where can one find free sensory nerve endings of skin

A

in the papillary dermis, epidermis, may be assoc with Merkel cells or hair follicles - pain, and fine touch

39
Q

What adnexa are found in the hypodermis

A

sebaceous glands and hair follicles and eccrine sweat glands

39
Q

Which plexus is found in the hypdermis

A

subcutaneous

40
Q

what is the purpose of AV shunts

A

they facilitate bypass of the subpapillary plexus to control body heat

42
Q

what structures of the skin are made of stratified cuboidal epithelium

A

ducts of sweat glands

43
Q

what is the functional structural unit of the skin

A

the keratinocyte