Integumentary Flashcards

1
Q

Fx of Integ Sys (6)

A

Protection,
Temp Reg,
Sensory Recep, Blood Reservoir,
Excrete/Absorption, Vit D

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2
Q

Epidermis c. type _____ epithelium of 4 types

A

Keratinized strat squamous epi,

Keratinocytes (90%)
Metalnocyte
Intraepidermal macrophage (Langerhans c.)
Tactile epithelial (Merkel c.)

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3
Q

Keratinocytes (3):

A

Keratin - tough fibrous protein
Lamellar granules (water-repellent sealant)
4-5 layer

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4
Q

Melanocytes

A

Melanin abs UV

Skin color

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5
Q

Intraepidermal/Langerhans c.

A

From bone marrow

recognize invaders

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6
Q

Merkel c.

A

Contact flattened processes of sensory neurons (touch sensations)
Deepest layer

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7
Q

Thin skin

A

Hairy, most regions, 4 layers

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8
Q

Thick skin (hairless)

A

Palms/Soles

Greater mechanical stress, 5 layers (+strata lucidum)

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9
Q

Layer of skin from superfiical to deep

A
Stratum Corneum
Stratum Lucidum
Stratum Granulosum (Necrosis starts)
Stratum Spinosum
Stratum Basale aka stratum germinativum
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10
Q

Stratum Basale (4)

A
Single row keratinocytes
Contains:
Stem c.
melanocyte
Merkels c.
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11
Q

Stratum Spinosum (3)

A

8-10 layers of keratinocytes
Intraepidermal macrophages
Melanocyte projection

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12
Q

Stratum Granulosum (2)

A

3-5 layer flattened, dying keratinocyte

w/ darkened granule (= lamellar granules = keratin precursor)

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13
Q

Stratum Corneum (2)

A

25-30 layer of thin dead keratinocyte

Extra layer = lucidum

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14
Q

Dermis contains (8) structures/cells

Two regions:

A
Fibroblast
Macrophage
Fat cell
Blood vess
Mm
Nerve
Glands
Hair foll (Arrector pili Mm attach)

Papillary
Reticular - “net-like”

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15
Q

Papillary Region of Dermis

Small _____ structures that project into ____ (layer of skin) which contains (3)

A

Nipple-shape, undersurface of epidermis called the Dermal Papillae

D.P
Blood vessel
Corpsucles of touch (Meissner’s)
Free N. endings

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16
Q

Reticular Region of Dermis

Attached to ______ layer (skin), contains (5)

A

Collagen-elastic fibers bundle

Att. Subcut layer
Fibroblast
Adipose c.
Hair foll, N. glandes

17
Q

Finger prints are _____

____ (direction) projection of the _____(skin layer) btw ____ (structure)

A

Epidermal ridge patterns

Downward pjt of Epidermis btw dermal papillae

18
Q

Epiderm Ridge Patter function (3)

A

Incr:
Friction w/ surface + derm pap (grip)
# of tactile receptor
Contact w/ blood vessel

19
Q

Skin color is mixture of 3 pigments & rel’d fx (pdn via___, stored in _____(layer)

A

Melanin - incr pdn via UV
Carotene, (yellow/orange) - stored in strat corneum
Hemoglobin

20
Q

Hair - surrounding structure (4)
Shaft has _____(shape) cells

Deep to superificial structure (think onion) (6)

A
Sebaceous gland
Apocrine sweat gland
Papilla (transition stage detach)
Hair root plexus
Shinglelike cuticle c.
Papilla/vessel, Hair Matrix (Melanocyte)
Medulla
Cortex
Cuticle
Dermal root sheath
21
Q

Hair Growth Cycle (3) & Descr

A

Anagen - Growth (85% scalp), yrs, hair length

Catagen (Regression/Transition) - days, hair follicle shrink, detaches from dermal papilla

Telogen & Exogen (Resting)

T - months, 10% hairs, old rests, new grows
E - Old sheds

22
Q

Hirutism vs Hpyertricosis

A

-Androgen depedent in female biology

Hypertricosis - excess hair growth not limited to androgen dependent

23
Q

Skin accessory glands (4) & function

A

Sebaceous (oil) - sebum, absent in palm/soles, some unrelated to follicle (lips/lids, ext. genitals)

Sudoriferous (sweat):

  • Eccrine (temperature).
  • Apocrine (after puberty, only in some areas/resp. to emotion/arousal)

Ceruminous (ear wax)

Mammary glands

24
Q

Eccrine absent in ____, #s in _____. Excretes _____ (3)

Sweat order:
Locations in sequence
Cold sweat order:

A

Absent in {lips/nail, eardrum genitals}. #s in palm/sole, fore. NaCl, ammonia, LAcid (waste)

Forehead> Body > Palm/sole.
Emotional (Cold): Palm/sole, axillae, body

25
Apocrine found in ____ (4) Color, contains chemical molecule
Axilla, groin area, Areolae of breast, bearded regions Milk/yellow, lipid & protein
26
Ceruminus Gland function (@)
Stick barrier, waterproof canal
27
Nails anatomy (5) Hyponychium
From proximal to distal: ``` Nail root - surrounded by matrix epithelium Epopnychium (cuticle), stratum corneum Lunula Nail body (plate) - below is nail bed. Free edge ``` Secure nail to fingertip
28
Fingernail Growth Facts (4) Toenail growth (2)
6 mths to regrow entire nail 50% faster in children Middle & index fastest, little slowest Pregnant faster 1 yr to regrow completely Big toenail grows fastest
29
Vit. D.: UV & enzymes activate molecule convert to _____, aids _____ in intestine Freq.
Calcitriol (hormone) active form of Vit D. Aids absorp of Ca. in intestine 15 min, 2x/wk
30
Skin aging starts at age____ Accelerated in_____ (demo) Mechanisms (6) Skin Hair Blood vessel Subcut
40 Smokers ``` Langerhans c. effectiveness decr. Sebaceous/sweat glands shrink/slow pdn Melanocytes decr. (greying) Blood vessel harden/thicken subcut adipose lost (thin skin), poor heal ``` 75% Men hair loss > 60
31
Epidermal Wound Healing Occurs when: ___ surrounding wound ____ until _____ (Hormone) stimulates mitoses
Abrasion/minor burn Basal c. migrate across until meet edges Epidermal gwth fac (gF)
32
Deep Wound Heal Occurs in ____ Phases (4)
Dermis & Subcut | Inflamm > Migra > Prolit > Maturation
33
Skin Cancer 3 maj type
: Basal c. carcinoma, Squamous carcinoma, Malig melanoma
34
Skin Burn caused by (4): Rule of 9s
Excess heat Electricity Radioactivity Corrosive chem on skin protein LE - 18%, UE - 9%, Trunk - 36%, Back 36%, Head &Neck: 9%