integumentary Flashcards
(40 cards)
skin comprises what percentage of total body weight
7%
Where are Langerhans cells most commonly found
stratum spinosum
the layers of the epidermis from most basal to most superficial are
germinativum, spinosum, granulosum, lucidum, corneum
what is the function of tonofilaments in the epidermis
they form keratin and attach intracellularly to desmosomes, hemidesmosomes
how many layers comprise the spinosum
8-10
What accounts for the spinosum’s distinct appearance
courser keratin
What non-keratinocytes are found in the spinosum
Langerhans and processes of melanocytes
desmosomes are most prominent at which epidermal layer
spinosum
major function of the stratum spinosum
strength and flexibility
how many layers make up the granulosum
3-5
At which layer are cells undergoing apoptosis
granulosum
what molecule causes the dark staining of granulosum kerationcytes
keratohyaline
what structure is responsible for waterproofing the skin
lamellar granules and their lipid-rich secretions (found in the stratum granulosum)
How many layers in stratum lucidum
4-6
How many layers in the stratum corneum
25-30
The layer that divides metabolically active cells and cells that have died
Granulosum
How long does the process of keratinizations from production to sloughing take? What influences this rate
4-6 weeks, epidermal growth factor
Which layer of the dermis is thickest and what fibers compose this layer
reticular layer - elastic and collagen
At what month of gestation do epidermal ridges form
3rd month
The two types of melanin
yellow/red pheomelanin and brown/black eumelanin
the two types of sudoriferous glands and their classification for secretion
eccrine and apocrine are both merocrine
What additional substances are secreted from apocrine glands (more so than eccrine)
lipids and protein
3 regions where sebaceous glands are found
hair, lips, glans penis, labia minora, tarsal glands of eyelids
The three portions of a hair
shaft root bulb