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Flashcards in Integumentary System Deck (220)
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1
Q

The first hairs-__- are fine, soft and lightly pigmented

A

Lanugo

2
Q

Some capillaries acquire muscular coats through the differentiation of ___ developing int he surrounding mesenchyme, and they become what

A

Myoblasts

Arterioles, arteries, venues, and veins

3
Q

Permanent third molar

A

13-25 years

4
Q

Lanugo begins to appear toward the end of the _ week and is plentiful by _ to _ weeks

A

12

17-20

5
Q

Eccrine gland secretions begin when? Apocrine sweat gland secretions begin when?

A

Shortly after birth

Puberty

6
Q

The central core of loosely arranged cells between he layers of the enamel epithelium is the __ __(__ __)

A

Enamel retinaculum (stellate retinaculum0

7
Q

Deciduous canine:

A

Erupt 16-20 mo

She’d 10-12 yrs

8
Q

Deciduous:second molar

A

Erupt 20-24 mo

Shed-10-12 yrs

9
Q

Congenital absence of one or more teeth is often a __ trait

A

Familial

10
Q

During the late fetal period, the epidermis at the site of origin of the primordial mammary gland becomes depressed, forming a shallow __ ___

A

Mammary pit

11
Q

The melanin produced by melanocytes is transferred tot he hair forming cells int he __ ___ several weeks before birth

A

Germinal matrix

12
Q

Molecular studies indicate that melanocyte-stimulating hormone cell surface receptor and melanosomal _-protein determining the degree of pigmentation by regulating __ ___ levels and activity

A

P

Tyrosine kinase

13
Q

The ___ is a superficial epithelial tissue that is derived from __ __ ___

A

Epidermis

Surface embryonic ectoderm

14
Q

Permanent canine

A

Erupt 1-12 yrs

15
Q

The arrector msucles are poorly developed int he hairs of the __ and certain parts of the __

A

Axilla

Face

16
Q

Deciduous:lateral incisor

A

Erupt 8-10 mo

She’d 7-8 yrs

17
Q

Later the melanoblasts migrate to the dermoepidermal junction and differentiate into ____

A

Melanocytes

18
Q

Capillary loops develop in some of the dermal ridges and do what

A

Provide nourishment for the epidermis

19
Q

The hemolysis associated with hemolytic disease of the neonate may produce- to _ discoloration of the teeth

A

Blue

Black

20
Q

Polymastia

A

Extra breast

21
Q

The periodontal ligament is derived from ___

A

NCC

22
Q

At first, the developing nail is covered by superficial layers of epidermis, the ___

A

Eponychium

23
Q

As each tooth bud is invaginated by mesenchyme, the primordium of the dental __ and dental __-the bud becomes cap chapped

A

Papilla

Follicle

24
Q

The ectodermal part of the developing tooth, the __ organ, eventually produces __

A

Enamel

Enamel

25
Q

Proliferation of cells in the stratum germinativum also produces __ __, which extend into the developing dermis

A

Epidermal ridges

26
Q

True angiomas as _ tumors of endothelial cells, usually composed of solid or hollow cords; hollow cords contain blood

A

Benign

27
Q

Sebaceous glands , independent of hair follicles, develop in a similar manner as buds of the ___ that invade the ___

A

Epidermis

Dermis

28
Q

As the dentin increases, it reduces the pulp cavity to a narrow __ __ through which the vessels and nerve pass

A

Root canal

29
Q

Teeth develop from the oral ___, ___ and ___

A

Ectoderm
Mesenchyme
NCC

30
Q

The thickening, U shaped bands -___ __- follow the curves of the primordial jaws

A

Dental laminae

31
Q

The blood vessels int he dermis differentiate from mesenchyme by ___

A

Vasculogenesis

32
Q

In enamel hypoplasia, various factors may injure ameloblasts such as what

A

Nutritional defiencies, tetracycline therapy, and infectious disease

33
Q

Macrodontia

A

Condition caused by the union of two adjacent tooth germs
Crowns of the two teeth can be partially of completely fused
Same applies to roots

34
Q

The permanent teeth develop in a manner similar to that described for the deciduous teeth. As a permanent tooth grows, the root of the corresponding deciduous tooth is gradually resorted by ___

A

Osteoclasts

35
Q

Glands are derived from the __ and grow into the __

A

Epidermis

Dermis

36
Q

At puberts in females, Growth of the duct and lobe systems also occurs because ofthe increased level of circulating __ and ___

A

Estrogen

Progesterone

37
Q

In the axillary and pubic regions, the lanugo is replaced at ___ by even courser __ __

A

Puberty

Terminal hairs

38
Q

As the root of the tooth grows its crown gradually erupts through the oral epithelium

A

The part of the oral mucosa around the erupted crown becomes the gingiva

39
Q

Dermatoglyphics

A

Looking at finger prints

40
Q

The central cells of the alveoli break down , forming an oily secretion ___

A

Sebum

41
Q

The outer cell layer of the enamel organ is the ___ enamel epithelium, whereas the inner cell layer lining the cap is the __ enamel epithelium

A

Outer

Inner

42
Q

Hair begins to develop during the _ to _ weeks, but become recognizable in the _ week

A

9, 12

20

43
Q

The hair grows through the epidermis on the eyebrows and the upper lip by the end of the _ week

A

12

44
Q

Why does albinism occur

A

Melanocytes do not produce melanin because of a lack of the enzyme, tyrosinase

45
Q

The dermis develops from __ underlying the surface ectoderm

A

Mesenchyme

46
Q

Dentinogenesis imperfecta

A

Common in Caucasian’s

Teeth are brown to gray blue, with an opalescent sheen

47
Q

Deciduous:medial incisor

A

Erupt 6-8 mo

She’d 6-7 yrs

48
Q

Odontogenesis is initiated by the inductive influence of the what

A

Neural crest-induced mesenchyme int he overlying ectoderm

49
Q

In males, where do they also get terminal hairs at puberty

A

Face and chest

50
Q

In females the mammary glands enlarge rapidly during __. Why

A

Puberty

Fat and other CT development int he breasts under the influence of estrodiol

51
Q

The mammary crests appear during the _ week but normally persist only int he pectoral area where the breasts develop

A

4

52
Q

The tooth buds for the permanent teeth appear at _ weeks fromt he deep continuations of the dental laminae

A

10

53
Q

What is the periodontal ligament

A

Specialized vascular CT that surrounds the root of the tooth, separating it from and attaching it to the alveolar bone

54
Q

The pattern of epidermal ridges that develop on the surface of palms and hands and soles of the feet is __ determined, and constitutes the basis for examining fingerprints (_)

A

Genetically

Dermtoglyphics

55
Q

As enamel increases, the ameloblasts regress toward the __ enamel epithelium

A

Outer

56
Q

At the end of the _ year, all 20 deciduous teeth are usually present

A

2

57
Q

The relative contents of melanin in the melanocytes accounts for the different colors of skin

A

Yup

58
Q

The buds for the second and third permanent molars develop __ birth

A

After

59
Q

The mandibular medial incisors-or _ incisors-usually erupt 6-8 months after birth, but maybe not until 12-13 months in some

A

Central incisors

60
Q

What causes amelogenesis imperfecta

A

Mutational defects of genes that encode for enamel, dentin, and mineralization

61
Q

What is the first indication fo toothe development

A

Thickening of the oral epithelium , a derivative of the surface ectoderm seen during the sixth week

62
Q

A child’s dentition contain _ deciduous teeth

A

20

63
Q

Later, the predentin calcified and becomes __

A

Dentin

64
Q

Angioma

A

Vascular anomalies in which transitory and/our surplus blood or lymphatic vessels persist

65
Q

Approximately 90% of males with __ syndrome have gynecomastia

A

Klinefelter

66
Q

The peripheral cells of the developing hair follicle form the __ __ __ and the surrounding mesenchymal cells differentiate into the __ ___ _

A

Epidermal root sheath

Dermal root sheath

67
Q

Toenails and fingernails begin to develop at the tips of the digits at approximately _ weeks

A

10

68
Q

The mammary bud grows down into the mesenchyme as a response to an __ influence of the mesenchyme

A

Inductive

69
Q

After birth, increased amounts of melanin are produced in response to _ light

A

UV

70
Q

Permanent lateral incisor

A

Erupt 8-9 yrs

71
Q

The epidermal ridges begin to appear in embryos at _ weeks are are permanently established at __ weeks

A

10

17

72
Q

The basal layer of the epidermis becomes the __ __, which produces new cells that are displaced into the more superficial layers

A

Stratum germinativum

73
Q

Each dental lamina develops _ centers of proliferation from which tooth buds grow into underlying ___

A

10

Mesenchyme

74
Q

The primordium of the epidermis is the __ ___

A

Surface ectoderm

75
Q

Cells of the inner enamel epithelium differentiate into ___, which produce enamel in the form of prisms over the dentin

A

Ameloblasts

76
Q

As skin grows, new capillaries grow out from the primordial vessels (_)

A

Angiogenesis

77
Q

What are neonate nipples like

A

Poorly formed and depressed

78
Q

In amelogenesis the teeth are covered with only a thin layer of abnormally formed enamel through which the color of the underlying dentin is visible, giving the teeth a darkened appearance

A

Rare AD condition

79
Q

Inheritance of dentinogenesis imperfecta

A

AD

80
Q

What causes enamel hypoplasia

A

Temporary disturbances of enamel formation

81
Q

Herlequin ichthyosis

A
Rare
AR
Mutation in ABCA12
Skin thickened, ridged, and cracked
70% die early
82
Q

The periodontal ligament is located between what

A

Cement or the root and the bony alveolus

83
Q

Amelogenesis imperfecta

A

Tooth enamel is soft and friable bc of hypocalcifciation and the teeth are yellow to brown in color

84
Q

Supernumerary nipples may be mistaken for __

A

Moles

85
Q

All ___ are extensively incorporated into the teeth

A

Tetracyclines

86
Q

Canalizations of the mammary buds is induced by what

A

Maternal sex hormones entering the fetal circulation

87
Q

Together, the dental papillla and enamel organ form the __ __

A

Tooth germ

88
Q

The inner cells of the dental sac differentiate into ____, which produce cement that is restricted to the root

A

Cementoblasts

89
Q

What is sebum

A

Substances released into hair follicle and passes to the surface of the skin. It mixes with desquamated peridermal cells to form the vernix caseosa

90
Q

The hair bulb is soon __ by a small mesenchymal hair papilla

A

Invaginated

91
Q

The cells in the surface ectoderm proliferate and form a layer of ___ epithelium, the __ and a __ layer

A

Squamous
Periderm
Basal

92
Q

Generalized albinism

A

AR

Sin hair and retina lack pigment

93
Q

The permanent molars have no deciduous predecessors;they develop as buds from posterior extensions of the __ __

A

Dental laminae

94
Q

When do secretions from apocrine glands start

A

Puberty

95
Q

What forms enamel pearls

A

Aberrant groups of emaloblasts

96
Q

The mesenchymal cells in the dental papilla adjacent to the inner enamel epithelium differentiate into ___, which produce ___ and deposit it adjacent to the epithelium

A

Odontoblasts

Predentin

97
Q

The epithelial root sheath grows into the mesenchyme and initiates __ formation

A

Root

98
Q

The peripheral cells of the secretory part of the sweat gland differentiate into ___ and ___ cells

A

Myoepithelial

Secretory

99
Q

The root of the tooth begins to develop after dentin and enamel formation is well __

A

Advanced

100
Q

As a result, the ducts of apocrine sweat glands open into the upper part of the hair follicles, superficial to the openings of the __ __

A

Sebaceous glands

101
Q

Permanent :medial incisor

A

Erupt 7-8 yrs

102
Q

The skin is characterized by __ and ___ , in ichthyosis

A

Dryness and scaling

103
Q

The buds grow into the surrounding CT and branch to form the primordia of the ___ and their associated ducts

A

Alveoli

104
Q

__/__ signaling also regulated many’s tage of tooth development

A

Wnt/B catenin

105
Q

Enamel hypoplasia

A

Defective enamel formation causes pits, fissures, or both in the enamel of the teeth

106
Q

The epithelial attachment of the developing sweat gland tot he epidermis forms the primordium of the __ __

A

Sweat duct

107
Q

The enamel is completely formed on all but the third molars by _ years of age

A

8

108
Q

Mammary buds begin to develop during the _ week as solid downgrowths of the epidermis into the underlying mesenchyme

A

6

109
Q

Abnormally shaped teeth common?

A

Yup

110
Q

Enamel overlies the yellowing dentin and does what

A

Protects it from being fractured

111
Q

In macrodontia, occasionally a tooth bud divides or two buds partially fuse to form fused teeth

A

Commonly observed int he mandibular incisors of the primary dentition, but it can also occur in the permanent dentition

112
Q

What does the integumentary system insist of

A

Skin and its appendages (nail, hair, sebaceous glands, and arrector msucles of hairs)
Mammary glands and teeth

113
Q

Tooth development occurs for __ after birth

A

Years

114
Q

Tooth buds develop into the __ teeth, which are shed during childhood

A

Deciduous

115
Q

Tetracyclines produce brownish-yellow discoloration (mottling) and enamel hypoplasia bc they interfere with the metabolic processes of the ____

A

Ameloblasts

116
Q

Cystic lymphangioma

Cystic hygromas

A

Angioma of lymphatics

117
Q

Lanugo is replaced during the perinatal period by coarser hairs that persist over __ of the body

A

Most

118
Q

The mammary glands develop similarly and are of the same structure in both sects

A

Ok

119
Q

Permanent Second premolar

A

11-12 yrs

120
Q

Permanent second molar

A

Erupt 12 yrs

121
Q

The internal part of each cap-shaped tooth, the dental ___, is the primordium of the dental pulp

A

Papilla

122
Q

As the deciduous teeth develop, they begin a continuous slow movement toward the oral cavity.

A

Ok

123
Q

Where are supernumerary teeth usually

A

Int he area of the maxillary incisors and may disrupt the position and eruption of normal teeth
Usually erupt posterior to normal teeth

124
Q

The hairs forming the eyebrows and eyelashes(cilia) have what kind of arrector msucles

A

NO ARRECTOR MSUCLES

125
Q

The exfoliated peridermal cells form part of a white, greasy substance-__ __-that covers the fetal skin

A

Vernix caseosa

126
Q

The primordia of the nails appear as thickened areas, or fields, of the epidermis at the tip of each digit

A

Later these nail fields migrate onto the dorsal surface carrying their innervation from the ventral surface.

127
Q

As the cellular bud elongates, its ends coil to form the primordium of the __ part of the gland

A

Secretory

128
Q

Enamel pearls

A

Spherical masses of enamel attached to the tooth

129
Q

Replacement of the peridermal cells continues until approximately the 21st week;thereafter, the periderm __ and the stratum corneum forms the __ __

A

Disappears

Stratum Lucidum

130
Q

The skin under the free margin of the nail is the _____

A

Hyponychium

131
Q

Arrector msucles of hairs, small bundles of smooth muscle fibers, differentiate from the mesenchyme surrounding the hair follicle and attach to the dermal root sheath and the papillary layer of the dermis

A

Ok

132
Q

The mammary buds develop from ___ ___, which are thickened strips of ____ extending fromt he axillary to the inguinal regions

A

Mammary crests

Ectoderm

133
Q

Foreign substance discolor teeth if they are incorporated into he developing enamel and dentin.

A

Discolored teeth

134
Q

What is the embryonic skin at 4-5 weeks

A

Single layer of surface ectoderm overlying mesoderm

135
Q

As the enamel organ differentiates, the developing tooth becomes _ shaped

A

Bell

136
Q

Each primary mammary bud soon gives rise to several secondary mammary buds that develop into the __ __ and their branches

A

Lactiferous ducts

137
Q

What is total anodontia associated with

A

Congenital ectodermal dysplasia

138
Q

Cells from the proximal nail fold grow over the nail field and __ to form the nail plate

A

Keratinize

139
Q

The lanugo help holds the __ on the skin

A

Vernix

140
Q

Ichthyosis

A

General term for a group of skin disorders resulting from excessive keratinization

141
Q

What is cement

A

Bone like, rigid CT covering the root of the tooth.

142
Q

The melanocytes begin producing __ before birth and distribute it to the epidermal cells

A

Melanin

143
Q

The mammary glands are modified and highly specialized types of _ glands

A

Sweat

144
Q

Development of _nails precedes _nails by 4 weeks

A

Finger

Toe

145
Q

The mandibular teeth usually erupt before the maxillary teeth. And __ teeth usually erupt sooner

A

Female

146
Q

The fibrous CT and fat of the mammary gland develop from the surrounding ____

A

Mesenchyme

147
Q

Usually, eruption of the deciduous teeth occurs between _ and _ months after birth

A

6

24

148
Q

Some fibers of the periodontal ligament are embedded int he _ of the root;other fibers are embedded int he __ __ of the alveolus

A

Cement

Bony wall

149
Q

When he deciduous tooth is shed, it consists only of the crown and the cervical, or uppermost part of the root

A

The permanent teeth usually begin to erupt during the 6th year and continue to appear until early adulthood

150
Q

Normal gynecomastiA

A

IN NEONATES bc of stimulation of the mammary glands by maternal sex hormones
Disappears in a few weeks

151
Q

Polythelia associated with what

A

Congenital defects, including renal and urinary tract anomalies

152
Q

The tooth is held in its ___ by the strong periodontal ligament, a derivative of the __ ___

A

Alveolus

Dental sac

153
Q

The dental sac is the primordium of what

A

Cement and periodontal ligament

154
Q

The nail fields are surrounded laterally and proximally by folds of the epidermis -___ __

A

Nail folds

155
Q

As the teeth develop and the jaws ossify, the outer cells of the dental sac also become active in bone formation

A

Each tooth soon becomes surrounded by bone, except over its crown

156
Q

Sensory nerve endings form in other ridges. The developing afferent nerve fibers apparently play an important role in what

A

Spatial and temporal sequence of dermal ridge formation

157
Q

The fingernails reach the fingertips at _ weeks;the toenails reach the tips of the toe at _ weeks

A

32 36

158
Q

Soon after birth, the nipples usually rise from the __ ___. Why

A

Mammary pits

Proliferation of the surrounding CT of the areola

159
Q

Maxillary lateral incisor teeth may have a slender , tapered shape

A

Peg shaped teeth

160
Q

For tooth discoloration(tetracycline), The critical period of risk is from approximately _ weeks of fetal life to the _ postnatal month for deciduous teeth and from _ weeks of fetal like to _ postnatal year for permanent teeth

A

14 10

14 16

161
Q

Angiomas of blood vessels ma be:

A

Arterial
Venous
Cavernous

162
Q

During puberty, approximately 2/3 of males have varying degrees of __ of breasts

A

Hyperplasia

163
Q

Partial anodontia

A

On or more teeth absent

164
Q

As the epidermal ridges form, the dermis projects into the epidermis, forming __ __

A

Dermal papillae

165
Q

Who should not be administered tetracycline

A

Pregnant women

Children younger than 8

166
Q

There are _ tooth buds in each jaw, one for each deciduous tooth

A

10

167
Q

As cells in the germinal matrix proliferate, they are pushed toward the surface, where they ___ to form __ __

A

Keratinization

Hair shafts

168
Q

This process continues until late gestation and by term, how many lactiferous ducts have formed

A

15-20

169
Q

Total anodontia

A

No teeth

Rare

170
Q

By 11 weeks, cells from the stratum germinativum have formed an ___ layer

A

Intermediate

171
Q

Apocrine sweat glands develop from downgrowths of the __ __ or the epidermis that give rise to the hair follicles

A

Stratum germinativum

172
Q

What causes dentinogenesis imperfecta

A

Failure of the odontoblasts to differentiate normally producing poorly calcified dentin

173
Q

Expression of what in the migrating NCC and ectoderm and mesenchyme is essential for the initiation of tooth development

A

MSX and Dlh(these two are HOX)

BMP, Tnf, Wnt, Shh, and FgF

174
Q

The enamel is derived from ___ and the oral cavity; all other tissue differentiate fromt he surrounding mesenchyme and NCC

A

Ectoderm

175
Q

The odontoblasts adjacent to the epithelial root sheath form dentin that is continuous with that of the __

A

Crown

176
Q

Polythelia

A

Extra nipple

177
Q

In dentinogenesis imperfecta both deciduous and permanent teeth are usually involved.

A

The enamel tends to wear down rapidly, exposing the dentin . A

178
Q

The myoepithelial cells are believed to be specialized smooth muscle cells that assist in expelling sweat from glands

A

Eccrine sweat glands begin to function shortly after birth

179
Q

The relative amounts of melanin accounts for different _ colors

A

Hair

180
Q

As the enamel organ and dental papilla develop, the mesenchyme surrounding the developing tooth condenses to form the __ __, a vascularized capsular structure

A

Dental sac

181
Q

The glands of skin include __ and ___ sweat glands, __ glands, and __ glands

A

Eccrine
Apocrine
Sebaceous
Mammary

182
Q

___ __ affects the differentiation fo the permanent teeth, resulting in incisors with central notches

A

Congenital syphilis

183
Q

Permanent first molar

A

Erupt 6-7 yrs

184
Q

__ arising during the critical period of permanent tooth development is the most common cause of enamel hypoplasia

A

Rickets

185
Q

Rickets is a disease in children who are deficient in vitamin _. It is characterized by disturbances of ossification of the epiphyseal cartilages and disorientation of cells at the metaphysis-section of bone between epiphysis and diaphysis

A

Metaphysics

186
Q

A hair follicle begins as a proliferation fo the __ __ of the epidermis and extends into the underlying ___

A

Stratum germinativum

Dermis

187
Q

Localized albinism/piebaldism

A

AD

Lack of melanin in patches of skin, hair or both

188
Q

Most of the mesenchyme that differentiates into the CT of the dermis originates from the __ layer of the ___ ___

A

Somatic

Lateral mesoderm

189
Q

The __, underlying the epidermis, is a deep layer composed of dense, irregular arranged CT that is derived from ___

A

Dermis

Mesenchyme

190
Q

Gynecomastia

A

Excessive development of male mammary tissue

191
Q

The eponychium ___, exposing the nail, except at its base ,where it persists as the ___

A

Degenerates

Cuticle

192
Q

__ is the hardest tissue in the body

A

Enamel

193
Q

Two sets of teeth normally develop

A

Deciduous teeeth

Permanent teeth

194
Q

What is the second hardest tissue int he body

A

Dentin

195
Q

Menaloblasts migrate into the __ __ and differentiate into ___

A

Hair bulbs

Melanocytes

196
Q

Collodion neonate

A

Covered by a thick, taut membrane that resembles collodion or parchment
Membrane cracks with first respiratory movement and falls off in large sheets
Shedding takes several weeks and normal appearing skin after

197
Q

Abnormal chromosome complements affect the development of the ridge patterns..example?

A

50% of neonates with downs have distinctive ridge patterns on their hands and feet that are of diagnostic value

198
Q

Polymastia or polythelia appear in what regions in females

A

Axillary or abdominal regions

199
Q

Permanent first premolar

A

Erupt 10-11 yrs

200
Q

Most sebaceous glands develop as buds from the sides of the developing __ ___ ___ of the hair follicles

A

Epidermal root sheaths

201
Q

By the end of the __ __, the blood supply of the fetal dermis is well established

A

First trimester

202
Q

The epithelial cells of the hair bulb constitute the __ _, which later produces the hair

A

Germinal matrix

203
Q

The inner and outer enamel epithelial come together in the neck of the tooth, where they form a fold, the __ ___ __-

A

Epithelial root sheath

204
Q

The central cells of the primordial ducts ___, forming a __

A

Degenerate lumen

205
Q

As the dentin thickens, the odontoblasts regress toward the center of the dental papilla;however their cytoplasmic processes-__ __-remain embedded in the dentin

A

Odontoblastic process

206
Q

Late in the embryonic period, ____ migrate into the mesenchyme in the developing dermis and differentiate into _____

A

NCC

Melanoblasts

207
Q

The first tooth buds appear iwhere. Later toothe development occurs where

A

Anterior mandibular region

Anterior maxillary region and progresses posteriorly in both jaws

208
Q

Eccrine sweat glands develop as epidermal downgrowths-__ __-underlying mesenchyme

A

Cellular buds

209
Q

The __ __ soon becomes a club shaped hair bulb

A

Hair bud

210
Q

By _ weeks, the mesenchymal cells have begun to produce collagenous and elastic CT fibers

A

11

211
Q

What does the vernix do

A

Protects the developing skin from constant exposure to amniotic fluid containing urine, bile salts, and sloughed cells

212
Q

What percent of the female population has polymastia or polythelia

A

.2-5.6

213
Q

Cement is deposited over the dentin of the root and meets the __ at the neck of the tooth

A

Enamel

214
Q

Hairs are first recognizable where

A

Eyebrows, upper lip, chin

215
Q

Th apocrine sweat glands are mostly confined to the __, ___ and __ regions and the __

A

Axillary, pubic, perineal, areolae around nipple

216
Q

Extra nipples of breasts develop alon the __ __

A

Mammary crest

217
Q

The cells of the periderm continually undergo ____ and ____ and are replaced by cells arising from the __ layer

A

Keratinization

Desquamtion

218
Q

Int erneralized albinism, what shows pigmentation

A

The iris

219
Q

Deciduous first molar

A

Erupt 12-16 mo

Shed-9-11 yrs

220
Q

The tooth buds for the permanent teeth appear at different dimes, mostly during the _ period

A

Fetal