Integumentary System Lecture Quiz 2 Flashcards
What are the 5 primary functions of the integumentary system?
- Physical protection from environmental hazards (toxins, microorganisms, UV rays)
- Helps regulate body temp. By controlling the rate of heat loss.
- Reduces water loss
- Synthesis and storage of lipids and vitamin D
- Coordination of immune response to pathogens and cancers in skin
Name the two layers that comprise the skin.
Epidermis and dermis
Name the third layer deep to the 2 layers of skin.
Subcutaneous layer
Name the type of tissue comprising the epidermis
Stratified squamous epithelium
What’s the lifecycle of epidermal cells, migration pattern, and physical changes? Include desmosomes, keratin proteins as they migrate superficially.
Skin cells (keratinocytes) replicate in the stratum basale. These living cells migrate superficially as more cells replicate in the stratum basale. The cells walls then thicken and more desmosomes form tightly around the cells walls. Then tough water proof proteins called keratin are laid down inside the cells. The end result is that the cells comprising the stratum cornerman make the skin tough and waterproof and fairly impervious to diffusion.
Describe where you would expect to find the blood supply (capillaries) for the epithelial cells in the previous micrograph and why. Label it in the micrograph.
The epidermis has no direct blood supply. It’s blood supply is in the dermis:deep to the stratum basale.
Where would you expect melanocytes to be located in the previous micrograph?
Stratum basale
What are the melanocytes primary function?
Melanocytes shield the keratinocytes nuclei from UV rays to prevent skin cancer. Melanocytes produce melanin, which resides in cellular extensions that extends around keratinocytes. The melanin diffuses out of the extensions and into the keratinocytes on the Sunday side of the nuclei. Thereby shielding the replicating DNA from potentially damaging UV rays.
All four types of tissues are found in the dermis. Which tissue is most abundant?
Connective tissue
Why do you think the dermis is mostly compromised of dense irregular, instead of regular connective tissue?
The multidirectional weave of the collagen fibers is designed to provide the skin with strength as it is pulled in many different directions.
What type of fiber found in the dermis provides it with its tensile strength in all directions?
Collagen
What type of fiber found in the dermis provides it with its elasticity?
Elastic
What cells produces the collagen and elastic fibers?
Fibroblast
Provide examples of where smooth and skeletal muscles are found in or attached to the dermis and what they do.
-Skeletal muscles in the face move the skin resulting in our facial expressions
-smooth muscle fibers are in the scrotum to help pull the testes up to the torso
-smooth muscle fibers attached to hair follicles make the hair stand up
-smooth muscle in dermal arterioles control blood flow in the capillaries.
The gel-like ground substance in the dermis maintains space between the collagen and elastic fibers, blood vessels and other skin accessory structures. The ground substance is an aqueous, gel-like packing material of the dermis. Describe the nutritional functions of the ground substance.
The aqueous nature of the ground substance permits easy diffusion of nutrients and waste products between cells and the capillaries.
The keratinocytes undergo structural changes as they migrate superficially. Describe changes to their intercellular keratin and desmosomes and how these affect their physical properties? Explain why these changes help the skin perform it’s first two functions.
The epidermal cells (keratinocytes) deposit more keratin internally (intracellularly) and increase the number of connections (desmosomes) between cells as they migrate superficially. The tough water/resistant protein (keratin) and tighter intercellular connections (desmosomes) cause the stratum Corneum to be water-resistant and relatively impermeable. So, toxins and pathogens tend not to be able to breech the epidermis.
Describe the blood vessel network in the epidermis, dermis and subcutaneous layer.
The network of small arteries that supply the skin and small veins that return the blood to the ventral circulation are generally at the depth of the junction between the dermis and subcutaneous layer. Branching off this network of supply and return vessels are connected to the venues through the capillaries to complete the circuit.
How do these billions of capillaries nourish and hydrate the cells in the skin?
The billions of capillaries in the skin keep it hydrated as plasma leaks (filtrates) out of them. Similarly nutrients such as glucose and white blood cells filtrate out of the capillaries and into the interstitial space, helping to keep the skin healthy. Waste products are taken up by the capillaries removing them from the skin.
Why would it be impractical to have blood vessels extend up into the epidermis?
Having no circulation in the epidermis reduces the risk of bleeding during daily activities or routine Skin injuries. This also reduces the risk of toxins and pathogens entering the blood stream.
Every living cells in our bodies requires energy to survive. Specifically where (organelle) in each cells is this energy produced?
Mitochondrion (singular)
Where in the file ling infrared image is best being lost fastest and slowest? Explain why.
Exposed skin (face neck and hands) is dissipating heat fastest. Skin covered by hair and clothing is still losing heat just more slowly.
What can we conclude then about the heat we produce and lose under various conditions such as rest exercise cool environments and warm environments?
Heat production and loss are equal.
What are two main types of connective tissue found in the subcutaneous layer?
Adipose and loose connective tissue
The skin is responsible for changing the rate of heat loss. How does the skin primarily regulate (increase and decrease) the rate of heat loss? Releasing sweat is only part of it. Consider the massive network of capillaries in the dermis.
The dermis regulates heat los primarily by constricting or dilating arterioles that supply the capillary bed. The massive network of vessels in the skin can be dilated to allow more warm blood to circulate through the skin. This increases the amount of body heat lost to the environment. Ex. During exercise when the muscles are producing an excess amount of heat the dermal arteries and arterioles dilate. Skin blood flow is decreased by constricting dermal blood vessels. This decreases the amount of warm blood circulating through the skin and decreases rate of heat loss. This is the typical response to conserve core body temp in cold environment. Various things such as sweating and removing clothing can further affect heat loss, but it is the regulation of dermal blood flow that fundamentally determines the rate of heat loss.