interpreting a coag screen Flashcards
1
Q
what factors form the intrinsic pathway?
A
factor 12, 11, 9 and 8
2
Q
what factor initiates the extrinsic pathway?
A
Factor 7
3
Q
what is the PT a measure of?
A
the time taken for blood to clot via the extrinsic pathway
4
Q
what is the INR?
A
a standardised version of the PT
5
Q
What does PT time indicate?
A
overall clotting factor synthesis
6
Q
What diseases can affect the PT?
A
liver disease
DIC
vitamin K deficiency
warfarin levels
7
Q
what is the APTT a measure of?
A
the time taken for blood to clot via the intrinsic pathway
8
Q
What does APTT time indicate?
A
overall clotting factor synthesis + individual clotting factor deficiency
9
Q
What diseases can affect APTT?
A
liver disease, DIC etc
also haemophilia + von Willebrand
