Interpreting Laboratory Tests Flashcards

1
Q

What are qualitative results?

A

yes/ no

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2
Q

What are semiquantitative results?

A

Negative (0)
Positive (1,2,3)

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3
Q

What are quantitative tests?

A

actual values:
units
amounts
concentrations
reaction rates

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4
Q

What is accuracy?

A

getting the right value

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5
Q

What is precision?

A

getting the same value every time

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6
Q

Where do we want “within run” and “without run” results to be?

A

within 5% of each other

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7
Q

What is “within run” and “without run” ?

A

calibrate devices using series of measurements with controls/ known analytes

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8
Q

How far off from true value is acceptable for lab testing (reference range)?

A

within 95% of 2 standard deviations

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9
Q

What is a statistically derived numerical range obtained by testing a sample of individuals in the lab area?

A

reference range

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10
Q

What factors affect reference range?

A

analytical
small reference sample
random vs nonrandom
skewed distribution
healthy vs not healthy
physiological factors

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11
Q

What are critical values?

A

far enough outside reference range that it indicated impending morbidity

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12
Q

What is a high critical value?

A

2-3 x upper normal limit UNL

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13
Q

What is a low critical value?

A

no guideline; go off symptoms

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14
Q

What is the reliability of a test to determine a positive result?

A

sensitivity

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15
Q

What is the reliability of a test to detect a negative result?

A

specificity

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16
Q

What agents can result in falsely high blood glucose?

A

Acetaminophen
CGMs

17
Q

What agents can result in false positives for amphetamines?

A

ranitidine
labetalol

18
Q

What agents can falsely prolong/ elevate prothrombin time and INR?

A

Daptomycin
Televancin

19
Q

How long does it take for a drug to reach steady state?

A

4-5 half-lives/ doses