Intracellular processes Flashcards Preview

Phase 1 week 1 - the skin > Intracellular processes > Flashcards

Flashcards in Intracellular processes Deck (15):
1

Describe the role of the golgi in protein trafficking

Protein is sent from the ER to the golgi. The proteins are carried in vesicles that fue to become cis cisterna. Proteins move through the golgi stack, undergoing enzymatic modification that labels them for a specific cell and destination

2

Describe the post office anaology of protein trafficking

Letter - new protein
Address label - Signal peptide
Postman - SRP receptor
Letterbox - translocon

3

What is added during glycolysation

Sugar residues (carbohydrates)

4

Where does glycolysation occur

In the golgi and ER

5

WHat is added during phosphorylation

A phosphate group

6

What does phosphorlyation do

It alters protein activity

7

What is added during Acetlyation

An acetyl group

8

What does acetylation do?

Regulates gene expression

9

Name 2 types of protein degredation

Lysosomal and proteosmal

10

Name 3 characteristics of lysosomal degredation

Occurs on membrane and extracellular proteins. Also occurs on protein with a long half life

11

Name 3 characteristics of proteosmal degredation

Occurs on proteins with a short half life, uses key metabolic enzymes abd takes place at proteosomes

12

Doe proteosmal degredation require ATP

yes

13

How does proteosmal degredation work?

3 steps - protein is tagged with ubiquitin

14

Name 3 pathways that culminate in lysosomal degredation

Endocytosis, phagocytosis and autophagy

15

What is autophagy

The consumption of the bodies own tissue