INTRACERLLULAR COMMUNICATION Flashcards

(39 cards)

1
Q

can be defined as the communication that
takes place within the cell.

A

Intracellular communication

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2
Q

The basis for the coordination of the physiological functions within a
multicellular organism is

A

intercellular signaling

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3
Q

Cells communicate through chemical signals, these chemical signals are
known as

A

ligands.

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4
Q

also called lipid-soluble ligands, can directly diffuse
through the plasma membrane and interact with internal receptors.

A

hydrophobic ligands

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5
Q

bind to the
extracellular domain of cell-surface receptors.

A

Water-soluble ligands

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6
Q

within the target cell must be coordinated, fine-tuned
and channeled within a network of intracellular signaling paths that finally
trigger distinct biochemical reactions and thus determine the specific functions
of a cell

A

Signal transduction

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7
Q

Tool for Intracellular Signaling (2)

A

Extracellular messengers
Gap junctions

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8
Q

Cells send out signals in the form of specific
messenger molecules that the target cell transmits into a biochemical
reaction.

A

Extracellular messengers

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9
Q

are channels that connect
two neighboring cells to allow a direct exchange of metabolites and signaling
molecules between the cells.

A

Gap junctions

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10
Q

Tool for Intracellular Signaling (2)

A

Cell–cell interaction via cell-surface proteins

Electrical signaling

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11
Q

A further intercellular communication mechanism relies
on electrical processes.

A

Electrical signaling

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12
Q

Another form of direct
communication between cells occurs with the help of surface proteins.

A

Cell–cell interaction via cell-surface proteins

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13
Q

Features of Cell Signaling (4)

A

Specificity
Amplification
Desensitization
Integration

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14
Q

the complementarity of structure between ligand and receptor binding contributes to the high specificity of the signaling pathway.

A

Specificity

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15
Q

During intracellular communication, the signal amplifies
several folds to generate the response.

A

Amplification

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16
Q

Also known as adaption, it is the condition that arises due to the continuous binding of the ligand to the receptor

A

Desensitization

17
Q

It can be defined as the ability of the system to receive multiple
signals and produce a unified response appropriate to the needs of the cell.

18
Q

Stages of Intracellular
Communication (3)

A

Reception
Transduction
Response

19
Q

It refers to receiving
the signal via ligand molecule
binding to the receptor.

20
Q

It refers to the
transfer of the signal from the cell surface to the interior of the cell, it is achieved by activating several proteins via phosphorylation,
dephosphorylation.

21
Q

A cell generates a
varying type of response according to the need, which result is the change in the metabolic activity of the cell.

22
Q

Forms of Cellular
Signaling (4)

A

Paracrine Signaling
Autocrine Signaling
Endocrine Signaling
Direct Cell Signaling

23
Q

Signals that act locally
between cells that are close
together

A

Paracrine Signaling

24
Q

a type of signaling where the
cell releases a chemical
molecule, which acts as a
ligand that binds to the
receptor on the cell that
produces it

A

Autocrine Signaling

25
It is a long-distance signaling pathway.
Endocrine Signaling
26
The ligands released in endocrine signaling are called
hormones
27
Gap junctions in animals and plasmodesmata in plants are connections between the plasma membranes of neighboring cells.
Direct Cell Signaling
28
Types of Receptors (5)
Cell Surface Receptor Enzyme Linked Receptor Ion Channel Linked Receptor G – Protein Linked Receptor Internal Receptor
29
also known as transmembrane receptors, are integral proteins that bind to external signaling molecules.
Cell Surface Receptor
30
are cell surface receptors with intracellular domains that are associated with an enzyme.
Enzyme-linked receptors
31
bind to a ligand and open a channel through the membrane that allows specific ions to pass through.
Ion Channel Linked Receptor
32
bind to a ligand and activate an associated G-protein
G – Protein Linked Receptor
33
also known as intracellular or cytoplasmic receptors, are found in the cytoplasm of target cells and respond to hydrophobic ligand molecules that are able to travel across the plasma membrane
Internal Receptor
34
Signaling Pathways and Signal Amplification (3)
Signaling Pathway Phosphorylation Second Messengers
35
After the ligand binds to the cell-surface receptor, the activation of the receptor’s intracellular components sets off a chain of events that is called a
Signaling Pathway
36
One of the most common chemical modifications that occurs in signaling pathways is the addition of a phosphate group to a molecule in a process called phosphorylation.
Phosphorylation
37
The transfer of the phosphate is catalyzed by an enzyme called a
kinase.
38
are small molecules that propagate a signal after it has been initiated by the binding of the signaling molecule to the receptor.
Second Messengers
39
The first messenger activates a Gprotein-linked receptor, which activates a specific G protein.
Cyclic AMP (cyclic adenosine monophosphate)