Intro to Immunology and Generalized Response to Infection

Question 1

Role of the immune system

Answer 1

1. kill or control pathogens
2. control disease
3. Repair tissue damage
4. organ development
5. maintain organ integrity and function

Question 2

Pathogens directly and indirectly damge tissues through

Answer 2

exotoxins and endotoxin

Question 3

Direct mechs of tissues damage by pathogens

Answer 3

• exotoxin production
• endotoxin
• direct cytopathic effect

Question 4

indirect mechs of tissues damage by pathogens

Answer 4

• immune complexes
• anti-host antibody
• cell-mediated immunity

Question 5

pathogen present the immune systsem with challenges

Answer 5

1. form diversity
2. life cycle diversity
3. diverse routs of infection
4. Rapid, targeted response over a broad domain

Question 6

(innate imm) Granulocytes cells

Answer 6

neutrophil
eosinophil
basophil
monocyte

Question 7

Adaptive immunity cells

Answer 7

B and T cells

Question 8

common lymphoid progenitor cells

Answer 8

T, B, plasmsa Cells? NK?

Question 9

common myeloid cells

Answer 9

neutrophil
eosinophil
basophil
monocyte
mast

Question 10

adaptive is common

Answer 10

lymphoid precursor

Question 11

innate is common

Answer 11

myeloid precursor

Question 12

lymphocytes are

Answer 12

active and in active T and B cells

Question 13

leukocytes are

Answer 13

innate and adaptive cells

Question 14

monocytes are

Answer 14

macrophages and dendritic

Question 15

Granulocytes are

Answer 15

neutrophil
eosinophil
basophil
mast

Question 16

____ are the primary response

Answer 16

neutrophils

Question 17

primary antigen presenting cells

Answer 17

dendritic
macrophage
B lymphocyte

Question 18

naive lymphocytes are activated in

Answer 18

lymph nodes

Question 19

humaral immunity is

Answer 19

antibodies released by b cells

Question 20

CD8 = MCH

Answer 20

I

Question 21

CD4 = MCH

Answer 21

II

Question 22

T cells are activated by

Answer 22

dendritic cell

Question 23

antigen presentation activates

Answer 23

lymphocytes

Question 24

CD8 T Cells:

Answer 24

cytotoxic

Question 25

CD4 T Cells:

Answer 25

Regulatory

Question 26

time/duration of innate for inflammation, complement activation, phago, destruction of path

Answer 26

minutes, days

Question 27

time/duration interaction between antigen presenting dend. and antigen specific T: recongnition of antigen, adhesion, co stim, T-cell prolif and diff

Answer 27

hours, days

Question 28

time/duration of activation of antigen-specific B cells

Answer 28

hours, days

Question 29

time/duration of formation of effector and memory t cells

Answer 29

hours, days

Question 30

time/duration of interaction of t cells with b cells, formation of germinal centers. formation of effector B cells and memory b cells. production of antibody

Answer 30

days, weeks

Question 31

time/duration of emigration of effector lymphocytes from peripheral lymphoid organs

Answer 31

a few days, weeks

Question 32

time/duration of effector cells and antibodies eliminate the pathogen

Answer 32

a few days, weeks

Question 33

time/duration of maintance of mem B and T cells

Answer 33

days-weeks, can be life long