Intro to Pharmacology Flashcards

(62 cards)

1
Q

Substance that causes a change in biological function

A

Drug

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2
Q

Pro-drug

A

Drug that is converted to its active form by biological processes in the body

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3
Q

Study of appropriate use of medications to treat

A

Pharmacotherapeutics

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4
Q

Study of genetic impact on drug metabolic processes that affect individual response

A

Pharmacogenomics

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5
Q

Methods to evaluate/compare value between therapies

A

Pharmacoeconomics

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6
Q

Study uses and effects of medications on large populations

A

Pharmacoepidemiology

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7
Q

Drugs that have the same action/class have what in common?

A

SUFFIX

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8
Q

Approximately how long does it take for a drug to develop in the US?

A

20 years

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9
Q

Describe the overall general pathway once a drug is administered?

A
  • Drug is distributed equally into circulation/tissues
    • Drug either metabolized and excreted OR concentrated at site of action
  • If at site: - - Effect OR Toxic
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10
Q

Pharmacokinetics deals with?

A

Time

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11
Q

Pharmacodynamics deals with?

A

Effect

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12
Q

What are the 2 major reasons for drug therapy failure?

A

Medication errors

Patient compliance

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13
Q

What is the Therapeutic Window?

A

Ratio between the Minimum Effective Concentration and the Minimum Toxic Concentration

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14
Q

When the Minimum Effective Concentration is reached, what occurs?

A

Effects! (Duration of the intended action)

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15
Q

ex. of drugs with small therapeutic windows (BAD)?

A

Warfarin, lithium, digoxin

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16
Q

IV

A

Intravenous

- MOST RAPID ONSET

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17
Q

IM

A

Intramuscular

- Can do large volumes but painful

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18
Q

SC

A

Subcutaneous

- Smaller volumes but painful

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19
Q

PO

A

Oral

- Most convenient and includes 1st pass effect

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20
Q

PR

A

Rectal

- Less 1st pass effect

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21
Q

Inhalation has a ____ onset

A

Rapid

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22
Q

Transdermal has a ____ absorption and _____ duration of action

A

SLOW absorption

PROLONGED duration of action

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23
Q

What is necessary to convert Acetomenophin out of its toxic form for it to be excreted?

A

Glutathione

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24
Q

ex. of Non-deleterious effects

A

Hair loss, itching, hair growth

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25
Deleterious effects are ____
TOXIC
26
SAME ingredients, dose, form, route etc.
Pharmaceutical Equivalance
27
Same drug but DIFFERENT complexes/salts/doses/forms
Pharmaceutical Alternatives
28
To be therapeutically equivalent, drugs must be?
Pharmaceutically equivalent with same effect and safety profile
29
Similar rate and extent of absorption with 80%-125% of reference product
Bioequivalence
30
Drugs that require a Rx are scheduled when?
There is potential for abuse
31
As you go from Schedule 1-5, what occurs?
Decreased risk for abuse
32
3 Pregnancy risk categories?
1. Pregnancy (labor and delivery) 2. Lactation (nursing moms) 3. Female and Male reproductive potential
33
q.d.
Daily
34
Daily
q.d.
35
b.i.d.
twice daily
36
twice daily
b.i.d.
37
t.i.d.
three times daily
38
three times daily
t.i.d.
39
q.i.d.
four times daily
40
four times daily
q.i.d.
41
q.o.d.
every other day
42
every other day
q.o.d.
43
q."#".h.
every # of hours
44
every 12 hours
q12h
45
q.a.m.
every morning
46
every morning
q.a.m.
47
q.p.m.
every evening
48
every evening
q.p.m.
49
q.h.s.
every night at bed time
50
every night at bed time
q.h.s.
51
p.r.n.
as needed
52
as needed
p.r.n
53
a.c.
before meals
54
before meals
a.c.
55
p.c.
after meals
56
after meals
p.c.
57
p.o.
by mouth
58
by mouth
p.o.
59
s.l.
under the tongue
60
under the tongue
s.l.
61
NGT and OGT
Naso-Gastric Tube | Oro-Gastric Tube
62
What is the dosage formula?
Docs order/supply on hand X Quantity(form)