Intro To RBF/GFR DSA Flashcards
Name some waste products that can be excreted by the kidneys
Urea Creatinine Acid Bilirubin Metabolites
How do kidneys respond to increase in water content
By increasing the output of water in the urine
What important blood pro-product do kidneys make
EPO
What is the stimulus for production of EPO
Decreased O2 in the Kidneys
The cortex of the kidney contains what
Corpuscles
Coiled blood vessels and coiled tubules
The medulla of the kidney contains what
Straight blood vessels and straight tubules
The kidneys receive aprox. How much CO
20%
The glomerular capillaries have what in terms of hydrostatic pressure
What about the peritubular capillaries
GC - high
PC - low
What is the purpose of the peritubular network
To reabsorb filtered fluid from the tubule lumen
What high hydrostatic pressure in the glomerular capillaries favors what
Filtration
Define vasa recta
Long medullary PTC
The rate and perfusion of renal blood flow in the kidney is highest and lowest where
Highest in the cortex
Lowest in the inner medulla
What do JG nephrons do
Secrete renin
What is the role of the PCT
Reabsorption of the largest fraction of glomerular filtrate
What is the role of the LoH
Urine concentration and secretion of Tamm-Horsfall Glycoprotein
What is the role of the DCT
Fine control of salt and water excretion
The podocytes are part of what in the glomerulus
The visceral part
What signals would cause vasoconstriction and lower GFR
NE
E
Endothelin
What signals would cause vasodilation and cause an increase in GFR
NO
Prostaglandin
ANP
DA
What does ANG II do to the GFR
Maintains it by selectively constricting efferent arterioles
Do systemic activation of the SNS due to baroreceptor reflexes (low P/BP) have much of an effect on RBF or GFR
No
ANG II effects which arteriole
Efferent
general SNS via a1 effects which arteriole most
Afferent
What produces the filtration slits
The podocytes
