Intro to the Pedigree Flashcards Preview

M2M Unit II > Intro to the Pedigree > Flashcards

Flashcards in Intro to the Pedigree Deck (16):
1

The _______ is the affected member through whom a family with a genetic disorder is brought to attention.

proband

1

Single-gene disorders (also called _____) often present with characteristic and recognizable patterns in pedigrees.

Mendelian disorders

1

genotype

the set of alleles that make up a genetic constitution (usually we are talking about a single locus)

1

The __________ is the set of alleles that make up a genetic constitution.

genotype

2

Single-gene disorders (also called Mendelian disorders) often present with _______.

characteristic and recognizable patterns in pedigree

3

Phenotype

the observable expression (of a genotype) as a morphological, clinical, cellular, or biochemical trait

5

_______ (also called Mendelian disorders) often present with characteristic and recognizable patterns in pedigrees.

Single gene disorders

6

____________ are couples who have >1 known ancestors in common.

Consanguineous matings

7

The __________ is the observable expression of a genotype.

phenotype

9

pedigree

graphical representation of the family tree

10

consanguineous matings

incest; Couples who have >1 known ancestors in common

12

A ______ is useful for identifying possible patterns of inheritance and estimating genetic risks to current and future family members

pedigree

13

proband

The affected member through whom a family with a genetic disorder is brought to attention

14

Why is a pedigree useful?

for identifying possible patterns of inheritance and estimating genetic risks to current and future family members

15

consultand

the person who brings the family to attention (can be affected or unaffected)

16

The __________ is the person who brings the family to attention (can be affected or unaffected).

consultand