Introduction Flashcards
Pathology
Study of diseases
Period of supernatural
Beliefs in the early times that diseases were due to supernatural forces
Period of humors
Diseases were attributed to accumulation of body humors
Period of abiogenesis
Diseases were believed to be spontaneous processes
Period of modern pathology
Causation of diseases clear due to new techniques ( autopsy, cell patho etc)
Who debunked the theory of abiogenesis
Louis Pasteur
Who showed that change at cellular level is basis of disease
Rudolf virchow
Clinical pathology
Study of disease based on observation of the patients
Experimental pathology
Observation of effects on experimental systems
Gross pathology
Naked eye appearance
Macroscopic appearance
Autopsy
Direct inspection and analysis of organs to determine the specific cause of death
Tissue processing steps
Fixation Impregnating Slicing Staining Mounting
Fixation of tissue role
Preserve the tissue in the state it was obtained
Solution used for Fixation
10% buffered Formalin
Substance used for impregnating tissue
Paraffin wax
What is a frozen section
Freezing a tissue to analyze it rapidly
Name of Routine staining
H&E
Disease definition
Presence of an abnormality leads to loss of normal health
List of Etiological agents of diseases
Genetically abnormality
Infectious agents
Chemicals
Physical agents
Primary / idiopathic disease
Cause of disease is unknown
Secondary disease
The cause of the disease is known
Risk factors of diseases
They are agents that make people more at risks of developing a specific disease ( like smoking etc )
Predisposition
Increased risk of having a disease
Can be genetic, environmental or infectious
Morbidity
The sum of effects of the disease of a person
