Introduction, definitions and nomenclature Flashcards
What is a primary
Name for where a cancer starts
What is metastasis
Secondary tumour (when the cancer spreads to other parts of the body)
What is tumour treatment based on
Knowledge of their pathology, biology and prognosis
Tumour proper name
Neoplasia
Definiton for neoplasm
abnormal mass of tissue, the growth of which exceeds, and is uncoordinated with that of normal tissue, and which persists in the same excessive manner after cessation of the stimulus which has evoked the change
Features of poorly differentiated malignant neoplasm
- Haphazard cellular arrangement
- Poor formation of gland lamina
- NUclei have variation in shape and size
Features of anaplastic or undifferentiated malignant neoplasm
- Bears no relation to normal epithelium
- No gland formation
- LArge variation in nuclei shape and size
What are well-differentiated tumour composed of
Cells which very closely resemble the cell of origin
What are poorly differentiated tumours composed of
Cells which bear little resemblance to the cell of origin, but just enough to enable the original cell type to be identified
What are undifferentiated or anaplastic tumours composed of
Cells which are so undifferentiated that their cell of origin is unknown
What is classification of a tumour based on
Histogenesis
Are all benign tumours harmless
No
How are the growth of benign tumours and malignant tumours different
Benign tumours grown by expansion whereas malignant grow by expansion and infiltration
How do benign and malignant tumours act on adjacent tissue
Benign compress adjacent tissue and malignant compress and invade adjacent tissue
What is metastasis
tumours spread to distant site
