Introduction lecture Flashcards

1
Q

what’s true about elements that are closer on the periodic table?

A

more similar

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2
Q

are we going to look at all elements on the periodic table for biochemistry?

A

there’s only certain elements that are involved

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3
Q

what is life composed of?

A

biological function
genes
proteins

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4
Q

what is molecular biology?

A

the interaction between genes and proteins

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5
Q

what is genetics?

A

the interaction between genes and biological function

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6
Q

what is biochemistry?

A

the interaction between proteins and biological function

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7
Q

is ATP incorporated into DNA?

A

yes

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8
Q

how much energy is released per mole of ATP?

A

30kJ

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9
Q

ATP equation

A

ATP + H2O –><– ADP + phosphate

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10
Q

Does ATP contain a lot of energy? How do you know?

A

not really, it can only sustain contraction in muscle for one second

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11
Q

If ATP can only sustain contraction in muscle for one second, how can it generate enough energy?

A

it’s part of an energy transfer system where ADP is transferred into ATP really quickly

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12
Q

how much ATP does someone synthesise in one day?

A

their own weight in ATP

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13
Q

how do we stay alive?

A

by ADP constantly being converted into ATP

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14
Q

give an example of something that acts as a reserve to rapidly regenerate ATP

A

phosphocreatine

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15
Q

what is phosphocreatine an example of?

A

a phosphate = important in biochemistry

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16
Q

what happens to phosphocreatine as you contract your muscles?

A

it runs down

17
Q

what happens when phosphocreatine has been used up after being used as a reserve to rapidly regenerate ATP?

A

we need to generate ATP in a new way

18
Q

diameter of the average atom

19
Q

significance of 1x10^-10

A

1 Angstrom (diameter of the average atom)

20
Q

1 Anstrom

A

1x10^-10m (diameter of the average atom)

21
Q

how large is a H2O molecule? explain

A

3x10^-10 (3 atoms across = must be about 3 Angstroms wide)

22
Q

size of a red blood cell

A

1x10^-5m across

23
Q

how can we see a red blood cell?

A

with an ordinary microscope

24
Q

how many red blood cells are in the body and what’s the significance of this?

A

10 trillion (1x10^13) more than any other human cell

25
what type of human cell are there the most of in the body?
red blood cells
26
what type of cells are there the most of in the body?
non-human cells
27
non-human cells that make up most of the body?
bacterial and archaeal cells
28
the microbiome
bacterial and archaeal cells
29
what do bacterial and archaeal cells make up?
the microbiome
30
stages in reaching Homo sapiens
earth formed prokaryotic (simplest) cells eukaryotic cells (e.g - algae) sexual reproduction (mixing genes between gametes revolutionised evolution) amphibians great apes genus homo Homo sapiens
31
what revolutionised evolution?
sexual reproduction - mixing genes between gametes
32
how many bases in the human genome?
3x10^9
33
what was the human genome project?
sequenced all the bases in the human genome
34
how long did the human genome project take?
15 years
35
how long does it take and how much does it cost to sequence a genome now?
15 hours much cheaper
36
give and explain two reasons why it was important to sequence the human genome in the HGP
with the genome, we could then translate the DNA into amino acids and then look at the sequence of amino acids in a protein and then could learn about the biological functions of proteins can also use sequences of DNA or amino acids to study disease (e.g - one amino acid mutated in haemoglobin = sickle cell anaemia)
37
what leads to sickle cell anaemia
one amino acid being mutated in haemoglobin