introduction to bone and soft tissue Flashcards
(35 cards)
what makes up the musculoskeletal system?
bone
muscle
connective tissue- tendon, ligaments and cartilage
how many bones does the adult human skeleton have?
206
how many bones do children have?
270
what is in the appendicular skeleton?
pectoral girdle
upper and lower limbs
pelvic girdle
what is in the axial skeleton?
cranium
vertebral column
rib cage
what are the 5 functions of the skeleton?
support protection movement mineral storage haematopoiesis
what are 2 components of bones?
cells
matrix
what are the bone cells?
osteogenic cell
osteoblast
osteoclast
osteocyte
what is the osteogenic cell?
stem cell
what is the osteoblast?
bone forming
secretes osteoid
catalyse mineralisation of osteoid
what is the osteocyte?
mature bone cell
formed when osteoblast imbedded in its secretions
sense mechanical strain to direct osteoclast and osteoblast activity
what is the osteoclast?
bone breaking
dissolve and resorb bone by phagocytosis
derived from bone marrow
where are osteogenic cells found?
deep layers of periosteum
where are osteoblasts found?
growing portions of bone including periosteum and endosteum
where are osteocytes found?
entrapped in matrix
where are osteoclasts found?
bone surfaces and at sites of old, injured or unneeded bone
how is the bone matrix split up?
organic(40%)(type 1 collagen and ground substance) and inorganic(60%)(calcium hydroxyapatite and osteocalcium phosphate) components
what makes up ground substance?
proteoglycans
glycoproteins
cytokine growth factors
what is an immature bone?
first bone that is produced
laid down in a woven manner- relatively weak
mineralized and replaced by mature bone
what is mature bone?
mineralized woven bone
lamellar (layer) structure- relatively strong
what are the 2 types of mature bone?
cortical
cancellous
what are the features of cortical bone?
compact- dense
suitable for weight bearing
what are the features of cancellous bone?
spongy- honeycomb structure
not suitable for weight bearing
what are osteons?
units of bone in compact bone
few spaces
provides protection, support and resists stresses produced by weight of movement