Introduction to Medical Virology and Diagnostic Methods

Question 1

Most virus are ___ limited

Answer 1

self

Question 2

Use of antiviral drugs and therapy is ___

Answer 2

limited

Question 3

Most virus are _symptomatic

Answer 3

asymptomatic

Question 4

What do we use to detect viral antigens?

Answer 4

Immunofluorescence and ELİSA

Question 5

What do we use to detect viral nucleic acids?

Answer 5

PCR or DNAT(NUCLEİC ACİD TEST)

Question 6

IgM usually indicates \_\_\_ infections but do not ALWAYS İNDİCATE İT.
may indicate
\_\_\_\_
\_\_\_\_
\_\_\_\_-

Answer 6

ACUTE
Re-infection
Re-activation
After an acute infection longer than expected

Question 7

What does seroconversion mean?

Answer 7

Increase in titer of virus-spesific ab(USUALLY IgG!!)

>4 FOLDS BTW SERUM SAMPLES COLLECTED İN ACUTE AND CONVALESCENTS PHASES

Question 8

For conformation of serologic assay results we use ___ and ____

Answer 8

Western Blot and RIBA

Question 9

What is the eclipse phase?

Answer 9

Period btw infection by a virus and appearance of mature virus within the cell(in this phase our immune system cannot detect this virus)

Question 10

What can we detect in eclipse phase?(EARLİER PHASE)

Answer 10

Nucleic Acid and Antigen