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Flashcards in Introduction to metabolism Deck (16):
1

Define: metabolism

all chem re's occuring in a cell/org in order to sustain life

2

metabolism is comprised of

catabolism and anabolism (and coupled by intermediates eg. ATP, NAD, NADH, FAD)

3

define: energy

capacity to do work

4

define: kinetic energy

energy of motion

5

define: potential energy

energy of state/position; including energy stored in chemical bonds

6

define: gibbs free energy

potential energy of a chemical system; amount of energy capable of doing work in a reaction

7

delta G, delta G0, delta G0'

free energy change
standard free energy change
standard free energy change at neutral ph and 5. M H2O

8

when K(eq)>1

delta G ' = neg, reaction goes forwardq

9

when K(eq)=1

delta G' = 0, equilibrium

10

when K(eq)<1,

delta G' = pos, reaction goes backwards

11

describe atp structure

3x phosphate groups + ribose sugar + adenine

12

why is hydrolysis of phosphodiester bonds very exergonic?

reduces the number of adjacent negative (hence repulsive) charges from 4 to 2/3
ADP and Pi are stabilised by resonace structures
H+ is a product, so the reaction is shifted forward, enhancing effects

13

how does ATP lower delta G of reactions

substitute reactions into each other.
final delta g is found by adding the first 2 delta g's

14

spontaneity of oxidation reactions?

very; but not necessarily quick ROR

15

spontaneity of hydrolysis reactions?

very

16

spontaneity of isomerisation reactions?

smaller (but still neg); for enantiomers its 0.