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NU 700 Pharm for Anes. > IV Induction Agents > Flashcards

IV Induction Agents Flashcards

1
Q

Propofol induction dose

A

1-2.5 mg/kg

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2
Q

Thiopental induction dose

A

3-5 mg/kg

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3
Q

Versed induction dose

A

0.1-0.3 mg/kg

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4
Q

Ketamine induction dose

A

1-2 mg/kg

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5
Q

Etomidate induction dose

A

0.2-0.4 mg/kg

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6
Q

Dex loading dose

A

1 mcg/kg

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7
Q

Dex maintenance dose

A

0.4-0.7 mcg/kg/hr

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8
Q

Propofol effect on SBP

A

Decrease

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9
Q

Thiopental effect on SBP

A

Decrease

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10
Q

Versed effect on SBP

A

minimal decrease

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11
Q

Ketamine effect on SBP

A

Increase

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12
Q

Etomidate effect on SBP

A

none

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13
Q

Dex effect on SBP

A

Decrease

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14
Q

Propofol effect on HR

A

None/minimal decrease

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15
Q

Thiopental effect on HR

A

Increase

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16
Q

Versed effect on HR

A

None

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17
Q

Ketamine effect on HR

A

Increase

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18
Q

Etomidate effect on HR

A

None

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19
Q

Dex effect on HR

A

Decrease

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20
Q

Propofol effect on SVR

A

Decrease

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21
Q

Thiopental effect on SVR

A

Decrease

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22
Q

Versed effect on SVR

A

Minimal/decrease

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23
Q

Ketamine effect on SVR

A

Increase

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24
Q

Etomidate effect on SVR

A

None

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25
Q

Dex effect on SVR

A

Decrease

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26
Q

Propofol effect on ventilation and RR

A

Decrease

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27
Q

Thiopental effect on ventilation and RR

A

Decrease

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28
Q

Versed effect on ventilation

A

None

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29
Q

Versed effect on RR

A

minimal/decrease

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30
Q

Ketamine effect on ventilation and RR

A

None

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31
Q

Etomidate effect on ventilation

A

Minimal/decrease

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32
Q

Etomidate effect on RR

A

Increase

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33
Q

Dex effect on ventilation and RR

A

None

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34
Q

Propofol effect on CO2 response

A

Decrease

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35
Q

Thiopental effect on CO2 response

A

Decrease

36
Q

Versed effect on CO2 response

A

Decrease

37
Q

Ketamine effect on CO2 response

A

None

38
Q

Etomidate effect on CO2 response

A

decrease

39
Q

Dex effect on CO2 response

A

none

40
Q

Propofol effects on CBF, CMRO2, ICP

A

Decrease

41
Q

Thiopental effects on CBF, CMRO2, ICP

A

Decrease

42
Q

Versed effects on CBF, CMRO2, ICP

A

CBF- decrease
CMRO2- decrease
ICP- no effect

43
Q

Ketamine effects on CBF, CMRO2, ICP

A

minimal/increase

44
Q

Etomidate effects on CBF, CMRO2, ICP

A

Decrease

45
Q

Dex effects on CBF, CMRO2, ICP

A

CBF- decrease
CMRO2- none
ICP- none

46
Q

Which drugs have anticonvulsant effects (4)

A

Prop
Thiopental
Versed
Ketamine?

47
Q

Which drugs provide anxiolysis (2)

A

Versed
Dex

48
Q

Which drugs provide analgesia (2)

A

Ketamine
Dex

49
Q

Which drug is assoc with emergence delirium

A

Ketamine

50
Q

Which drug is assoc with N/V

A

Etomidate

51
Q

Which drugs are assoc with adrenocortical suppression (2)

A

Etomidate
Versed?

52
Q

Which drugs cause pain with injection (2)

A

Prop
Etomidate

53
Q

Which IV drug causes histamine release

A

Thiopental

54
Q

Propofol infusion dose

A

25-300 mcg/kg/min
25-75 sedation
100-300 general anes.

55
Q

Propofol onset

A

30-60 sec

56
Q

Propofol duration

A

patient/dose dependent
5-15 mins

57
Q

Propofol distribution half life

A

2-4 mins

58
Q

Propofol elimination half life

A

1-5 mins

59
Q

Propofol clearance rate

A

25ml/kg/min

60
Q

Propofol vol of distribution

A

2-8L/kg

61
Q

Propofol protein binding

A

98%

62
Q

Etomidate onset

A

30-100 sec

63
Q

Etomidate duration

A

5-15 min

64
Q

Etomidate distribution half life

A

2.7 min

65
Q

Etomidate redistribution half life

A

29 mins

66
Q

Etomidate elimination half life

A

3-5.3 hours

67
Q

Etomidate protein binding

A

77% (albumin)

68
Q

Versed elimination half time

A

1.9 hours

69
Q

Versed peak

A

5.6 mins

70
Q

Versed duration

A

15-80 mins

71
Q

Remimazolam induction dose

A

2.5-5 mg/kg

72
Q

Remimazolam maintenance dose

A

1.25-2.5 mg q2min

73
Q

Flumazenil initial dose

A

0.2 mg

74
Q

Flumazenil subsequent doses

A

0.1mg q1m

75
Q

Which agents are imidazole rings

A

etomidate
dex

76
Q

Which agent is an aklylphenol

A

propofol

77
Q

which agent is an arylcyclohexylamine

A

ketamine

78
Q

Ketamine protein binding

A

12%

79
Q

Ketamine IM induction dose

A

4-8 mg/kg

80
Q

Ketamine onset

A

3-5 min

81
Q

Ketamine elimination half time

A

2-3 hours

82
Q

Dex distribution half life

A

6 min

83
Q

Dex elimination half life

A

2 hours

84
Q

Dex context sensitive half time

A

4-250 min

85
Q

Dex onset

A

10-30 mins

86
Q
A
87
Q

Dex duration

A

10-30 mins

NU 700 Pharm for Anes. (6 decks)

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