IV. Surface Modifications Flashcards

1
Q

Surface coatings

A
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2
Q

Bioactive surface functionalization - 3 steps

A
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3
Q

Bioactive surface functionalization - Proteins diffuses freely at distance of > 2nm

A
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4
Q

Bioactive surface functionalization - Protein can bind reversibly (adsorption) and release (desorption) directly at the interface

A
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5
Q

Bioactive surface functionalization - Bound prot. can change structurre to maximize surface interactions

A
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6
Q

Bioactive surface functionalization - All materials adsorb bioolecules in varying amounts due to:

A
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7
Q

Bioactive surface functionalization - Control of physical adsorption of biomolecules

A
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8
Q

Bioactive surface functionalization - Introducing charges to biomaterials surface

types

A
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9
Q

Bioactive surface functionalization - Introducing charges to biomaterials surface

Exposure to oxidizing agent

A
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10
Q

Bioactive surface functionalization - Introducing charges to biomaterials surface

Plasma treatement

A
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11
Q

Bioactive surface functionalization - Introducing charges to biomaterials surface

Plasma treatement

methods

A
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12
Q

Bioactive surface functionalization - Introducing charges to biomaterials surface

Coating with a charged polymer

A
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13
Q

Bioactive surface functionalization - Limitations of physical adsorption

A
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14
Q

Bioactive surface functionalization - Covalent coupling of biomolecules to materials (=chemical adsoroption)

A
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15
Q

Bioactive surface functionalization - Covalent coupling of biomolecules to materials (=chemical adsoroption)

Types

A
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16
Q

Bioactive surface functionalization - (Bio-)conjugation chemistry

17
Q

Bioactive surface functionalization - Silanization of biomaterials

18
Q

Bioactive surface functionalization - Surface coupling of biomolecules using a spacer

19
Q

Bioactive surface functionalization - Comparison of surface immobilization strategies

20
Q

Bioactive surface functionalization - bioinspired strategies

21
Q

Bioactive surface functionalization - bioinspired strategies

Nacre

22
Q

Bioactive surface functionalization - bioinspired strategies

Mussle adhesion and DOPA

23
Q

Surface passivation-antifouling - Motivation

24
Q

Surface passivation-antifouling - Facts

25
Surface passivation-antifouling - How to avoid protein adsorption
26
Surface passivation-antifouling - Self assembled monolayers (SAM)
27
Surface passivation-antifouling - Supported lipid bilayers (SLB)
28
Surface passivation-antifouling - Polymer brushes-entropic penalty
29
Surface passivation-antifouling - Polymer brushes-entropic penalty | Grafting to
30
Surface passivation-antifouling - Polymer brushes-entropic penalty | Example PLL-g PEG
31
Surface passivation-antifouling - Polymer brushes-entropic penalty | Grafting from
32
Surface passivation-antifouling - Other anti-adhesive polymer architecures
33
Stability and degradability