IVT Flashcards
(20 cards)
Why IVT ?
Direct administer drug to local
Minimal Side effect
What type of drug we delivery to IVT ?
Anti VEGF
Steroid
ATB
List an Anti VEGF
Bevaciumab - Avastin
Ranibizumab - Lucentis
Afliberceot - Eylea
Brolucizumab - Beovu
Faricimab - Vabysmo
Indications of An-ti VEGF
Wet AMD
DME
RVO
Myopic CNV
NVG
Endopthalmitis drug ?
Vancomycin
Ceftazidime
Steroid use in ?
Uveitis
DME
RVO
Injection Protocol for Wet AMD ?
- Loading phase monthly x 3 mo
- T and E if stable extend 2 wks
4 6 8 10 - Pro Re Nata - Monitor Monthly - if worsen inject
- Fixed dosing - Eylea
( VIEW 8 wk after loading )
Injection Protocol for DME ?
DRCR.net protocol T
- Aflibercept 5 monthly then PRN or T&E
- Ranibizumab 4-6 monthly the PRN or T & E
- Bevacizumab 4-6 monthly then PRN or T&E
Second line of DME ?
Steroid
- Ozurdex - one implant , 3-6 mo in duration
- Iluvien - one implant , 36 mo
Used if
- non respond to Anti VEGF
- pseudophakic
RVO injection protocol ?
Lucentis or Eylea monthly x 3-6 mo then PRN or T&E
Ozurdex 1 inject every 3 - 4 mo
mCNV injection protocol ?
Lucentis / Avastin : 1 injection
PER RADIANCE
IVT ATB ?
Vancomycin 1 mg
Ceftazidime 2.25 mg
Drug use in preparation before IvT
5% Povidone - Iodine .
Equipment use in IVT ?
- Lid Retractor
- Caliper : 3.5 mm , 4 mm
- 30G or 32G needle
Injection site ?
Pseudophakic : 3.5 mm
Phakic 4 mm
Suptemp or inf temp
Injection technique ?
- Mark site
- 30G needle up 90 degree sclerA
- Inject , withdraw with cotton tip
- Post inejction
What to observe post injection ?
1.Red eye
2.Floater
3.Eye pain
4.VA drop
Dosage of IVT Ganiclovir
2 mg in 0.05 ml
Key complication of Brolucizumab ?
IOI + Vasculitis
Common Pathogen Post IVT Endopthalmitis
S.Epidermidis
