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Total bilirubin above ____ means it's not physiologic jaundice and you need to investigate further.

above 15 mg/dL


When does physiologic jaundice appear and when does it go away?

Appears at 24 hours after birth and is gone by 1 week of life (2 weeks if preterm infant)


Visible jaundice with total serum bilirubin above 5 mg/dL BEFORE 24 hrs of age usually means what?

significant hemolysis, e.g. Rh incompatibility, spherocytosis, G6PD deficiency


Name 5 causes of nonhemolytic unconjugated hyperbilirubinemia.

1. enclosed hemorrhage, e.g. cephalohematoma
2. polycythemia
3. bowel obstruction
4. UDPGT deficiency (enzyme that conjugates bilirubin)
5. Gilbert syndrome


What are the treatments for unconjugated hyperbilirubinemia?

1. phototherapy with blue-green light
2. exchange transfusion (for severe)