Joe + Sathya Flashcards

(30 cards)

1
Q

Are hands sterile?

A

no they are aseptic

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2
Q

What is asepsis?

A

absence of microbes that cause disease

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3
Q

What is surgically clean?

A

destruction of all accessible microorganisms on the surface

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4
Q

What is contaminated?

A

a surface or structure where microbes are present

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5
Q

When is an infection considered a surgical infection?

A

30 days after regular surgery, 1 year after implant

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6
Q

HOw does anesthesia enourage infection?

A

hypotension and hypothermia decrease perfusion and reduce defence against infection

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7
Q

How much does each hour increase infection chance?

A

30%. higher risk for contamination and more suppressed immune system

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8
Q

How much does each hour increase infection chance?

A

30%. higher risk for contamination and more suppressed immune system

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9
Q

What % of gloves have holes to start? after surgery?

A

1.5% before, 26% after.

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10
Q

What % of gloves have holes to start? after surgery?

A

1.5% before, 26% after.

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11
Q

What are adhesions?

A

scar tissue that forms between organs and tissue after an abdominal surgery.

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12
Q

why aren’t small animals prone to adhesions?

A

they have an active fibrolytic system

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13
Q

What causes adhesions

A

fibrin deposition after an abdominal inflammatory response.

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14
Q

Most common reason to get a horse back in sugary?

A

adhesion

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15
Q

Most common reason to get a horse back in sugary?

A

adhesion, specifically small intestine lesion adhesions (which cause death)

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16
Q

What are the risk factors for adhesions?

A
SMALL INTESTINAL LESIONS!
prolonged post-op ilius
Repeated exploratories
Young animals
peritonitis and abscesses 
inflammation
ischemia
foreign material
Tight sutures
Intestinal distention
17
Q

What are the risk factors for adhesions?

A
SMALL INTESTINAL LESIONS!
prolonged post-op ilius
Repeated exploratories
Young animals
peritonitis and abscesses 
inflammation
ischemia
foreign material
Tight sutures
Intestinal distention
18
Q

Adhesion formation is the balance between:

A

coagulation and fibrinolysis - if we increase coagulation (as in inflammation) we decrease fibrinolysis

19
Q

what factor breaks down fibrin?

A

Tissue plasminogen activator (TPA)

20
Q

When do adhesions become permanent (fibrer)

A

1-2 weeks after surgery.

21
Q

Which adhesions rarely cause clinical problems

A

fibrinous, omental,

22
Q

which adhesions cause clinical problems?

A

fibrous adhesions

23
Q

Adhesions: omentum, intestine to mesentary/peritoneium, intestine to intestine, multiple intestine to intestine. Rank from worst to best.

A

ometum, intestine to peritoneum, intestine to intestine, multiple. (massive fiberous)

24
Q

How do you prevent adhesions?

A

minimize inflammation, enhance fibrinolysis, stimulate intestinal motility.

25
How do you prevent adhesions?
``` aseptic technique!! minimize inflammation (be gentle, don't let bleed, remove damaged tissue, minimize suture, no powdered gloves, keep bowel moist, don't expose mucosa or suture), enhance fibrinolysis, stimulate intestinal motility. ```
26
How do you prevent adhesions? 7
- aseptic technique!! - minimize inflammation (be gentle, don't let bleed, remove damaged tissue, minimize suture, no powdered gloves, keep bowel moist, don't expose mucosa or suture), - end the surgery with an abdominal lavage to rinse contaminants and inflammatory factors + fibrin. - Belly Jelly - bioresorbable membrane - anticoagulants (increases Tpa and enhances fibrinolysis) - prevent ilius (lidocaine)
27
How do you treat a less severe adhesion?
can manage medically and with diet
28
How do you manage severe restrictive adhesions?
- remove devitalized intestine and break down adhesions surgically
29
survival rate of horses with adhesions?
0-20%
30
which plasminogen activator is the key regulator of fibrinolysis?
Tissue plasminogen activator!!