Journal of Veterinary Diagnostic Investigation Flashcards

(24 cards)

1
Q

A domestic rabbit presents with signs of gastrointestinal stasis. A blood glucose measurement using a human portable glucometer (PGM) reads 22 mmol/L. Which interpretation is most appropriate based on recent studies in rabbits?
A. This reading indicates mild hyperglycemia and requires no immediate concern.
B. Blood glucose >20 mmol/L in rabbits may indicate a poor prognosis in cases of GI obstruction.
C. Human PGMs are not capable of detecting hyperglycemia in rabbits accurately.

A

B. Blood glucose >20 mmol/L in rabbits may indicate a poor prognosis in cases of GI obstruction.

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2
Q

A 1-year-old ferret presents with chronic weight loss and intermittent diarrhea with undigested food particles. Histology shows a lymphoplasmacytic infiltrate in the intestines. What is the most likely diagnosis?
A. Ferret coronavirus infection
B. Inflammatory bowel disease (IBD)
C. Gastrointestinal lymphoma

A

B. Inflammatory bowel disease (IBD)

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3
Q

A domestic ferret was diagnosed with cryptococcosis. Genetic typing identified VGII of Cryptococcus gattii. What is the most likely source of infection?
A. Transmission from another infected ferret
B. Contaminated water
C. Environmental exposure to decaying wood or soil contaminated with bird droppings

A

C. Environmental exposure to decaying wood or soil contaminated with bird droppings

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4
Q

A rabbit shows signs of severe cachexia and histological examination of bone marrow reveals replacement of hematopoietic tissue with glycosaminoglycan-rich material. What is the most likely diagnosis?
A. Myelofibrosis
B. Gelatinous transformation of the bone marrow
C. Lymphoid depletion

A

B. Gelatinous transformation of the bone marrow

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5
Q

You are performing rotational thromboelastometry (ROTEM) in a New Zealand White rabbit. Which factor should be carefully controlled during sample rest time prior to analysis?
A. Sample pH
B. Ambient humidity
C. Rest temperature

A

C. Rest temperature

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6
Q

A pet rabbit presents with respiratory distress and a mediastinal mass. Histology confirms a type A thymoma. What is the most appropriate treatment approach?
A. Chemotherapy
B. Radiation therapy
C. Surgical excision

A

C. Surgical excision

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7
Q

A domestic ferret presents with persistent pancytopenia and weight loss. Histopathology reveals systemic pyogranulomatous inflammation. What is the most likely diagnosis?
A. Ferret systemic coronavirus disease
B. Lymphoma
C. Aleutian disease

A

A. Ferret systemic coronavirus disease

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8
Q

Several mink on a Utah farm show respiratory illness. PCR confirms H1N1 influenza A virus. What is the most likely source of infection?
A. Contaminated water
B. Infected human handlers
C. Wild birds

A

B. Infected human handlers

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9
Q

What is a reliable method for detecting rabbit hemorrhagic disease virus (RHDV) in field conditions using minimal sample?
A. Serum sample via venipuncture
B. Nasal swab
C. Blood filter paper and ear punch sample

A

C. Blood filter paper and ear punch sample

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10
Q

Which virus is most commonly responsible for white-spotted liver lesions in wild European rabbits in Spain?
A. Rabbit hemorrhagic disease virus
B. Eimeria stiedae
C. Hepatitis E virus

A

B. Eimeria stiedae

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11
Q

A rabbit outbreak in the southwestern United States is associated with high mortality. What is the causative agent?
A. Pasteurella multocida
B. Rabbit hemorrhagic disease virus 2
C. Francisella tularensis

A

B. Rabbit hemorrhagic disease virus 2

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12
Q

Which hematologic method was found equivalent to manual differential counts in rabbits?
A. ADVIA 2120 analyzer
B. CBC5 Hemavet
C. QBC Vet Autoreader

A

A. ADVIA 2120 analyzer

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13
Q

A pet degu presents with a neck mass. Histopathology reveals a thymic epithelial tumor. Where is this tumor most likely originating?
A. Thoracic thymus
B. Cervical thymus
C. Mediastinal lymph node

A

B. Cervical thymus

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14
Q

An African pygmy hedgehog presents with labored breathing and dies shortly after. Necropsy reveals bronchopneumonia due to which uncommon viral agent?
A. Canine adenovirus 1
B. Skunk adenovirus 1
C. Hedgehog herpesvirus

A

B. Skunk adenovirus 1

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15
Q

Which of the following tumor types has been documented in naked mole-rats?
A. Osteosarcoma
B. Chordoma
C. Fibrosarcoma

A

B. Chordoma

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16
Q

A degu presents with a coccygeal mass. Histopathologic examination reveals physaliferous cells and a myxoid matrix. What is the most likely diagnosis?
A. Osteochondroma
B. Lipoma
C. Chordoma

17
Q

A rabbit presents with oral masses. Histopathologic analysis most often reveals:
A. Fibrosarcoma
B. Squamous cell carcinoma
C. Epulis

A

B. Squamous cell carcinoma

18
Q

Which virus group is best studied using molecular methods for detection in rabbits and hares?
A. Myxoma virus
B. Rabbit hemorrhagic disease viruses
C. Poxviruses

A

B. Rabbit hemorrhagic disease viruses

19
Q

Which technique helped identify the environmental source of Cryptococcus gattii in a ferret case?
A. Soil culture only
B. PCR and multilocus sequence typing
C. Histological staining

A

B. PCR and multilocus sequence typing

20
Q

Which histologic grading system was proposed for IBD in ferrets?
A. Modified WSAVA scoring
B. Custom 0–3 grade based on inflammation severity and distribution
C. Canine-based simplified 2-tier system

A

B. Custom 0–3 grade based on inflammation severity and distribution

21
Q

What blood parameter is crucial for prognostic assessment in critically ill rabbits?
A. Total protein
B. Glucose
C. Hematocrit

22
Q

What condition is indicated by gelatinous marrow transformation in rabbits?
A. Severe infection
B. Starvation and fat mobilization
C. Bone neoplasia

A

B. Starvation and fat mobilization

23
Q

What explains the advantage of ROTEM over PT/aPTT in rabbits?
A. Shorter test duration
B. Use of platelet-rich plasma
C. Whole-blood assessment of hemostasis

A

C. Whole-blood assessment of hemostasis

24
Q

Which clinical sign is associated with ferret IBD?
A. Hematuria
B. Bruxism and drooling
C. Hind limb paralysis

A

B. Bruxism and drooling