Kahoot

Question 1

What are factors that can help Leptospira spread?

Answer 1

Hemolysin
Endotoxins
Decreased phagocytosis
Cell mediated sensitivity to antigen

Question 2

What specimens to we collect for Leptospira testing?

Answer 2

CSF
Blood

Question 3

What specimens are inoculated directly into laboratory media and why?

Answer 3

Urine
Yield is much higher after the first week of illness

Question 4

What antibiotics are Leptospires susceptible to?

Answer 4

Streptomycin
Tetracycline
Doxycycline
Macrolides

Question 5

Which drug is best for treating Leptospira?

Answer 5

Tetracyclines

Question 6

What stage of syphilis do we see macular rash in the palms and soles of feet?

Answer 6

Secondary stage

Question 7

What is Weil’s disease caused by?

Answer 7

Leptospira

Question 8

What disease is characterized by hepatic and renal failure and intravascular disease?

Answer 8

Weil’s disease

Question 9

What do Spirochaetales contain?

Answer 9

Leptospira
Borrelia
Treponema

Question 10

What does Borrelia burgdorferi cause?

Answer 10

Lyme disease
NA and EU

Question 11

What does B. recurrentis, duttonii, and hermsii cause?

Answer 11

Relapsing fever
Tick borne (Endemic)
Louse borne (Epidemic)

Question 12

What genus are arthropods the vector for?

Answer 12

Borrelia

Question 13

What are pinta, syphilis, and yaws caused by?

Answer 13

Treponema

Question 14

What tests can we use to diagnose syphilis?

Answer 14

Darkfield microscopy
Rapid plasmin reagin (RPR)

Question 15

What do spirochetes use to move?

Answer 15

Periplasmic flagella

Question 16

In what stage of syphilis do we see granulomatous lesions in the skin, bones, and liver?

Answer 16

Tertiary stage

Question 17

How is congenital syphilis acquired?

Answer 17

Intrauterine infection (Treponemes crossing the placenta)

Question 18

Why do we use Enzyme immunoassay (EIA) when testing for syphilis?

Answer 18

Simple to perform
Commercially available
Inexpensive (Book does not say this)

Question 19

What is the primary method used for the laboratory diagnosis of syphilis?

Answer 19

Serologic tests

Question 20

What are two examples of Non-treponemal tests?

Answer 20

Venereal disease research lab (VDRL)
Rapid plasma reagin (RPR)

Question 21

How do we characterize early onset congenital syphilis?

Answer 21

Osteochondritis
Anemia
Hepatosplenomegaly

Question 22

What are the two growth cycles of chlamydia?

Answer 22

Elementary body (EB)
Reticulate body (RB)

Question 23

What does an infection of Chlamydia cause in newborns?

Answer 23

Conjunctivitis
Pneumonia
Nasopharyngeal infection

Question 24

What is an infection of the lymph nodes near the genital tract causing bubo formations?

Answer 24

Lymphogranuloma Venereum (LGV)

Question 25

What causes Rocky Mountain Spotted Fever?

Answer 25

R. rickettsia

Question 26

What causes Louse borne typhus?

Answer 26

R. prowazekii

Question 27

What can the direct cytologic method rapidly detect?

Answer 27

Ocular infection in newborns

Question 28

What are the clinical manifestations of Chlamydia trachomatis?

Answer 28

Lymphogranuloma Venereum (LGV) Trachoma Urogenital infections

Question 29

What specimens do we use for Chlamydia pneumonia?

Answer 29

Sputum BAL Nasopharyngeal Throat swabs

Question 30

What organism do arthropods transmit?

Answer 30

Rickettsia

Question 31

How do urological infections of Chlamydia manifest in women?

Answer 31

PID Endometritis Salpingitis Urethritis

Question 32

What is C. pneumonia also a risk factor for?

Answer 32

Gulliain-Barre syndrome

Question 33

What does not cause the traditional fourfold rise in antibody titer between acute and convalescent specimens?

Answer 33

Chlamydia trachmatis

Question 34

What do we use serologic testing for to isolate antibodies because it is difficult to isolate?

Answer 34

Chlamydophila pneumoniae

Question 35

What does C. psittaci cause?

Answer 35

Parrot fever

Question 36

How do urogenital infections of chlamydia manifest in men?

Answer 36

Nongonoccocal urethritis (NGU) Prostatitis Epididymitis

Question 37

What organism causes Murine/Endemic Typhus?

Answer 37

Rickettsia typhi

Question 38

What test is used to detect IgM and IgG for Mycoplasma

Answer 38

Enzyme Immunoassay (EIA)

Question 39

How is Mycoplasma able to colonize the genital and respiratory tracts?

Answer 39

Adheres tightly to mucosal surfaces Prevents elimination

Question 40

What does Mycoplasma pneumoniae cause?

Answer 40

Primary atypical pneumonia

Question 41

What causes reproductive disorders and is found in many sexually active women?

Answer 41

U. ureolyticus

Question 42

What stain can we see to better detect Mycoplasma colonies?

Answer 42

Diene’s stain

Question 43

What kind of environment does Mycoplasma grow in?

Answer 43

Anaerobic Capnophilic Ambient Air

Question 44

What was Ureaplasma urealyticum previously known as?

Answer 44

T-strain Mycoplasma

Question 45

Why do we add penicillin in the transport of Mycoplasma?

Answer 45

It is resistant and reduces bacterial contamination

Question 46

What DNA fluorescent stain is used for organisms that lack a cell wall?

Answer 46

Acridine orange (Flag for review)