Flashcards in Katzung 12th ed - Chapter 50 - Metronidazole, Disinfectants (2) Deck (9):
Name some anaerobes that are susceptible to metronidazole.
Bacteroides, Clostridium, Trichomonas, Giardia, Amoebiasis.
Describe the distribution of metronidazole in tissues.
Metronidazole is widely distributed, and penetrates well into CSF.
What is the route of metabolism of metronidazole?
Name some routes of administration of metronidazole (up to four)
Oral, IV, rectal suppository, vaginal gel (for vaginitis).
Half-life of metronidazole?
One side effect of metronidazole?
Metallic taste in the mouth.
What is the definition of an antiseptic?
An antiseptic is a disinfectant with sufficiently low toxicity to allow use directly on the skin, mucous membranes and wounds.
What is autoclaving?
Sterilisation using pressurised steam at 120 degrees for 20 minutes.