Ketorolac

Question 1

Ketorolac Class

Answer 1

NSAID

Nonselective COX 1 and 2 inhibitor

Question 2

Ketorolac Dose

Answer 2

15 mg

Dose decreased in elderly and CKD

Question 3

Ketorolac Onset and DOA

Answer 3

Onset: 30 min | DOA: 4 hours

Question 4

Ketorolac Uses

Answer 4

Pain control, esp during emergence

Question 5

Ketorolac Metabolism

Answer 5

Hepatic

Question 6

Ketorolac Excretion

Answer 6

Renal (60% unchanged)

Question 7

Ketorolac Advantages

Answer 7

Decrease post-operative opioid requirements

Low incidence of nausea and vomiting

Lack of respiratory depression

Question 8

Ketorolac Ortho Considerations

Answer 8

Bone healing delays by NSAIDs, not used in ortho surgery, OK with stable and healing fracture

Question 9

Ketorolac Respiraotry Considerations

Answer 9

Caution in patients with asthma r/t bronchoconstriction d/t decrease leukotriene productions

Question 10

Ketorolac Renal Considerations

Answer 10

Caution in patients with renal disease r/t renal vasoconstriction d/t decrease prostaglandin production

Question 11

Ketorolac Neurosurgery Considerations

Answer 11

Bleeding risk in intracranial surgery